LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Imatinib
10
uM
LJP6
 2
N13
 72
hr
 1311 4256 4961 0.8578 0.8464
MDA-MB-231 Imatinib
10
uM
LJP6
 3
N13
 72
hr
 1311 4552 4973 0.9152 0.9099
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1311 4559 4870 0.9361 0.9314
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 1311 4639 4961 0.9350 0.9312
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 1311 4767 4973 0.9584 0.9563
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 1311 4343 4870 0.8918 0.8825
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 1311 3893 4961 0.7846 0.7626
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 1311 4096 4973 0.8235 0.8079
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 1311 3896 4870 0.8000 0.7775
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 1311 3888 4961 0.7836 0.7614
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 1311 3967 4973 0.7976 0.7781
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 1311 3041 4870 0.6244 0.5594
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 1311 2652 4961 0.5345 0.4431
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 1311 2827 4973 0.5684 0.4908
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 1311 1510 4870 0.3101 0.0772
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 1311 1422 4961 0.2866 0.0430
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 1311 1455 4973 0.2925 0.0554
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 1311 1170 4870 0.2402 -0.0586
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 1311 1034 4961 0.2084 -0.1166
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 1311 950 4973 0.1910 -0.1545
MDA-MB-231 CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 1311 902 4870 0.1852 -0.1795
MDA-MB-231 CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 1311 962 4961 0.1939 -0.1492
MDA-MB-231 CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 1311 919 4973 0.1848 -0.1689
MDA-MB-231 CGP60474
0.04
uM
LJP5
 1
F06
 72
hr
 1311 3800 5128 0.7410 0.7173
MDA-MB-231 CGP60474
0.04
uM
LJP5
 2
F06
 72
hr
 1311 4070 5100 0.7980 0.7825