LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 1311 1358 5128 0.2648 0.0178
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 1311 1585 5100 0.3108 0.1014
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 1311 1379 5010 0.2752 0.0262
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1311 1452 5128 0.2831 0.0530
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1311 1652 5100 0.3239 0.1250
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1311 1439 5010 0.2872 0.0491
MDA-MB-231 Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 1311 1394 5128 0.2718 0.0314
MDA-MB-231 Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 1311 1531 5100 0.3002 0.0821
MDA-MB-231 Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 1311 1332 5010 0.2658 0.0080
MDA-MB-231 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1311 4912 4870 1.0086 1.0090
MDA-MB-231 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1311 4507 4961 0.9084 0.9023
MDA-MB-231 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1311 5140 4973 1.0334 1.0345
MDA-MB-231 Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 1311 4924 4870 1.0110 1.0116
MDA-MB-231 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 1311 4425 4961 0.8918 0.8842
MDA-MB-231 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 1311 5182 4973 1.0419 1.0431
MDA-MB-231 Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 1311 5125 4870 1.0523 1.0546
MDA-MB-231 Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 1311 4593 4961 0.9257 0.9212
MDA-MB-231 Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 1311 4974 4973 1.0000 1.0000
MDA-MB-231 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 1311 4967 4870 1.0199 1.0209
MDA-MB-231 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 1311 4450 4961 0.8969 0.8898
MDA-MB-231 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 1311 5086 4973 1.0226 1.0233
MDA-MB-231 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 1311 5013 4870 1.0293 1.0308
MDA-MB-231 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 1311 4719 4961 0.9511 0.9484
MDA-MB-231 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 1311 5409 4973 1.0875 1.0892
MDA-MB-231 Imatinib
10
uM
LJP6
 1
N13
 72
hr
 1311 4574 4870 0.9392 0.9348