LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD7762
1.11
uM
LJP6
 3
L03
 72
hr
 1311 1245 4973 0.2503 -0.0268
MDA-MB-231 AZD7762
3.33
uM
LJP6
 1
L02
 72
hr
 1311 814 4870 0.1671 -0.2228
MDA-MB-231 AZD7762
3.33
uM
LJP6
 2
L02
 72
hr
 1311 793 4961 0.1598 -0.2307
MDA-MB-231 AZD7762
3.33
uM
LJP6
 3
L02
 72
hr
 1311 750 4973 0.1508 -0.2523
MDA-MB-231 AZD7762
10
uM
LJP6
 1
L01
 72
hr
 1311 807 4870 0.1657 -0.2264
MDA-MB-231 AZD7762
10
uM
LJP6
 2
L01
 72
hr
 1311 636 4961 0.1282 -0.3142
MDA-MB-231 AZD7762
10
uM
LJP6
 3
L01
 72
hr
 1311 705 4973 0.1417 -0.2760
MDA-MB-231 AZD8055
0.04
uM
LJP6
 1
A12
 72
hr
 1311 2959 4870 0.6076 0.5370
MDA-MB-231 AZD8055
0.04
uM
LJP6
 2
A12
 72
hr
 1311 3231 4961 0.6512 0.5995
MDA-MB-231 AZD8055
0.04
uM
LJP6
 3
A12
 72
hr
 1311 2568 4973 0.5163 0.4182
MDA-MB-231 AZD8055
0.12
uM
LJP6
 1
A11
 72
hr
 1311 2151 4870 0.4417 0.2987
MDA-MB-231 AZD8055
0.12
uM
LJP6
 2
A11
 72
hr
 1311 2546 4961 0.5131 0.4127
MDA-MB-231 AZD8055
0.12
uM
LJP6
 3
A11
 72
hr
 1311 2051 4973 0.4124 0.2617
MDA-MB-231 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 1311 1923 4870 0.3949 0.2240
MDA-MB-231 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 1311 2141 4961 0.4315 0.2908
MDA-MB-231 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 1311 1881 4973 0.3782 0.2062
MDA-MB-231 AZD8055
1.11
uM
LJP6
 1
A09
 72
hr
 1311 1783 4870 0.3661 0.1761
MDA-MB-231 AZD8055
1.11
uM
LJP6
 2
A09
 72
hr
 1311 2131 4961 0.4295 0.2877
MDA-MB-231 AZD8055
1.11
uM
LJP6
 3
A09
 72
hr
 1311 1902 4973 0.3824 0.2132
MDA-MB-231 AZD8055
3.33
uM
LJP6
 1
A08
 72
hr
 1311 1995 4870 0.4096 0.2480
MDA-MB-231 AZD8055
3.33
uM
LJP6
 2
A08
 72
hr
 1311 1847 4961 0.3723 0.1952
MDA-MB-231 AZD8055
3.33
uM
LJP6
 3
A08
 72
hr
 1311 1778 4973 0.3575 0.1714
MDA-MB-231 AZD8055
10
uM
LJP6
 1
A07
 72
hr
 1311 1395 4870 0.2864 0.0331
MDA-MB-231 AZD8055
10
uM
LJP6
 2
A07
 72
hr
 1311 1780 4961 0.3588 0.1724
MDA-MB-231 AZD8055
10
uM
LJP6
 3
A07
 72
hr
 1311 1513 4973 0.3042 0.0771