LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 1311 2566 4961 0.5172 0.4185
MDA-MB-231 AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 1311 2707 4973 0.5443 0.4576
MDA-MB-231 AT-7519
0.37
uM
LJP6
 1
K04
 72
hr
 1311 948 4870 0.1947 -0.1577
MDA-MB-231 AT-7519
0.37
uM
LJP6
 2
K04
 72
hr
 1311 856 4961 0.1725 -0.1994
MDA-MB-231 AT-7519
0.37
uM
LJP6
 3
K04
 72
hr
 1311 937 4973 0.1884 -0.1605
MDA-MB-231 AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 1311 787 4870 0.1616 -0.2366
MDA-MB-231 AT-7519
1.11
uM
LJP6
 2
K03
 72
hr
 1311 687 4961 0.1385 -0.2861
MDA-MB-231 AT-7519
1.11
uM
LJP6
 3
K03
 72
hr
 1311 761 4973 0.1530 -0.2466
MDA-MB-231 AT-7519
3.33
uM
LJP6
 1
K02
 72
hr
 1311 646 4870 0.1326 -0.3122
MDA-MB-231 AT-7519
3.33
uM
LJP6
 2
K02
 72
hr
 1311 613 4961 0.1236 -0.3272
MDA-MB-231 AT-7519
3.33
uM
LJP6
 3
K02
 72
hr
 1311 580 4973 0.1166 -0.3458
MDA-MB-231 AT-7519
10
uM
LJP6
 1
K01
 72
hr
 1311 558 4870 0.1146 -0.3634
MDA-MB-231 AT-7519
10
uM
LJP6
 2
K01
 72
hr
 1311 502 4961 0.1012 -0.3937
MDA-MB-231 AT-7519
10
uM
LJP6
 3
K01
 72
hr
 1311 513 4973 0.1031 -0.3863
MDA-MB-231 AZD7762
0.04
uM
LJP6
 1
L06
 72
hr
 1311 4506 4870 0.9252 0.9195
MDA-MB-231 AZD7762
0.04
uM
LJP6
 2
L06
 72
hr
 1311 4410 4961 0.8888 0.8809
MDA-MB-231 AZD7762
0.04
uM
LJP6
 3
L06
 72
hr
 1311 4488 4973 0.9023 0.8959
MDA-MB-231 AZD7762
0.12
uM
LJP6
 1
L05
 72
hr
 1311 2860 4870 0.5872 0.5096
MDA-MB-231 AZD7762
0.12
uM
LJP6
 2
L05
 72
hr
 1311 2791 4961 0.5625 0.4820
MDA-MB-231 AZD7762
0.12
uM
LJP6
 3
L05
 72
hr
 1311 2924 4973 0.5879 0.5172
MDA-MB-231 AZD7762
0.37
uM
LJP6
 1
L04
 72
hr
 1311 2503 4870 0.5139 0.4070
MDA-MB-231 AZD7762
0.37
uM
LJP6
 2
L04
 72
hr
 1311 2330 4961 0.4696 0.3490
MDA-MB-231 AZD7762
0.37
uM
LJP6
 3
L04
 72
hr
 1311 2459 4973 0.4944 0.3865
MDA-MB-231 AZD7762
1.11
uM
LJP6
 1
L03
 72
hr
 1311 1256 4870 0.2579 -0.0227
MDA-MB-231 AZD7762
1.11
uM
LJP6
 2
L03
 72
hr
 1311 1205 4961 0.2429 -0.0432