LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3
LJP5
 3
N22
 72
hr
 2543 5992 5760 1.0401 1.0678
SK-BR-3
LJP5
 3
N23
 72
hr
 2543 5273 5760 0.9153 0.8555
SK-BR-3
LJP5
 3
N24
 72
hr
 2543 4878 5760 0.8468 0.7369
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 1311 5273 5128 1.0282 1.0285
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 1311 5063 5100 0.9928 0.9926
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 1311 5225 5010 1.0427 1.0438
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 1
J05
 72
hr
 1311 5026 5128 0.9800 0.9796
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 2
J05
 72
hr
 1311 4986 5100 0.9777 0.9771
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 1311 5042 5010 1.0062 1.0064
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 1
J04
 72
hr
 1311 5016 5128 0.9781 0.9776
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 1311 4587 5100 0.8994 0.8947
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 1311 4933 5010 0.9845 0.9839
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 1
J03
 72
hr
 1311 4895 5128 0.9545 0.9532
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 2
J03
 72
hr
 1311 4503 5100 0.8829 0.8769
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 3
J03
 72
hr
 1311 4631 5010 0.9242 0.9201
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 1311 4578 5128 0.8927 0.8878
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 1311 4532 5100 0.8886 0.8830
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 1311 4643 5010 0.9266 0.9227
MDA-MB-231 Seliciclib
10
uM
LJP5
 1
J01
 72
hr
 1311 2834 5128 0.5526 0.4794
MDA-MB-231 Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 1311 2607 5100 0.5112 0.4199
MDA-MB-231 Seliciclib
10
uM
LJP5
 3
J01
 72
hr
 1311 2675 5010 0.5338 0.4456
MDA-MB-231 AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 1311 3988 4870 0.8189 0.7996
MDA-MB-231 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 1311 4019 4961 0.8100 0.7921
MDA-MB-231 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 1311 3954 4973 0.7950 0.7750
MDA-MB-231 AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 1311 2555 4870 0.5246 0.4223