LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 2
B20
 72
hr
 1311 3473 4961 0.7000 0.6608
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 3
B20
 72
hr
 1311 3650 4973 0.7339 0.7027
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 1
B19
 72
hr
 1311 1189 4870 0.2441 -0.0506
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 2
B19
 72
hr
 1311 1329 4961 0.2679 0.0068
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 3
B19
 72
hr
 1311 998 4973 0.2007 -0.1325
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 1311 1240 4870 0.2546 -0.0293
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 1311 1098 4961 0.2213 -0.0885
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 1311 1431 4973 0.2877 0.0463
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 1311 2490 5128 0.4855 0.3852
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 1311 2484 5100 0.4871 0.3853
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 1311 2141 5010 0.4273 0.2884
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 1
I05
 72
hr
 1311 913 4870 0.1875 -0.1743
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 2
I05
 72
hr
 1311 971 4961 0.1957 -0.1450
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 3
I05
 72
hr
 1311 813 4973 0.1635 -0.2202
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 1
D05
 72
hr
 1311 1262 5128 0.2461 -0.0195
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 2
D05
 72
hr
 1311 1148 5100 0.2251 -0.0658
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 3
D05
 72
hr
 1311 1277 5010 0.2549 -0.0138
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 1311 951 4870 0.1953 -0.1563
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 1311 983 4961 0.1981 -0.1396
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 1311 816 4973 0.1641 -0.2188
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 1311 954 5128 0.1860 -0.1495
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 1311 966 5100 0.1894 -0.1446
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 1311 861 5010 0.1718 -0.1957
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 1
I03
 72
hr
 1311 955 4870 0.1961 -0.1544
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 2
I03
 72
hr
 1311 789 4961 0.1590 -0.2327