LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 1311 4357 5128 0.8496 0.8410
MDA-MB-231 Neratinib
0.37
uM
LJP5
 2
A16
 72
hr
 1311 4479 5100 0.8782 0.8717
MDA-MB-231 Neratinib
0.37
uM
LJP5
 3
A16
 72
hr
 1311 4251 5010 0.8484 0.8369
MDA-MB-231 Neratinib
1.11
uM
LJP5
 1
A15
 72
hr
 1311 4475 5128 0.8726 0.8661
MDA-MB-231 Neratinib
1.11
uM
LJP5
 2
A15
 72
hr
 1311 4164 5100 0.8165 0.8034
MDA-MB-231 Neratinib
1.11
uM
LJP5
 3
A15
 72
hr
 1311 4284 5010 0.8549 0.8443
MDA-MB-231 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 1311 3723 5128 0.7260 0.6995
MDA-MB-231 Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 1311 3808 5100 0.7467 0.7229
MDA-MB-231 Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 1311 3491 5010 0.6967 0.6590
MDA-MB-231 Neratinib
10
uM
LJP5
 1
A13
 72
hr
 1311 2784 5128 0.5429 0.4661
MDA-MB-231 Neratinib
10
uM
LJP5
 2
A13
 72
hr
 1311 2999 5100 0.5880 0.5252
MDA-MB-231 Neratinib
10
uM
LJP5
 3
A13
 72
hr
 1311 3039 5010 0.6065 0.5442
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 1
B24
 72
hr
 1311 4084 4870 0.8386 0.8223
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 2
B24
 72
hr
 1311 4177 4961 0.8419 0.8284
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 3
B24
 72
hr
 1311 4305 4973 0.8655 0.8553
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 1
B23
 72
hr
 1311 4378 4870 0.8989 0.8905
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 2
B23
 72
hr
 1311 4645 4961 0.9362 0.9325
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 3
B23
 72
hr
 1311 4382 4973 0.8810 0.8725
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 1
B22
 72
hr
 1311 3974 4870 0.8160 0.7962
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 2
B22
 72
hr
 1311 4476 4961 0.9021 0.8955
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 3
B22
 72
hr
 1311 4099 4973 0.8241 0.8086
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 1
B21
 72
hr
 1311 3617 4870 0.7427 0.7091
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 2
B21
 72
hr
 1311 4011 4961 0.8084 0.7902
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 3
B21
 72
hr
 1311 3900 4973 0.7841 0.7624
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 1
B20
 72
hr
 1311 3307 4870 0.6790 0.6301