LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 3
I03
 72
hr
 1311 889 4973 0.1787 -0.1832
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 1
D03
 72
hr
 1311 1003 5128 0.1956 -0.1275
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 2
D03
 72
hr
 1311 880 5100 0.1726 -0.1843
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 1311 969 5010 0.1934 -0.1450
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 1311 891 4870 0.1830 -0.1848
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 1311 923 4961 0.1860 -0.1673
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 1311 810 4973 0.1629 -0.2217
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 1311 934 5128 0.1821 -0.1586
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 1311 972 5100 0.1906 -0.1419
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 1311 964 5010 0.1924 -0.1473
MDA-MB-231 Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 1311 708 4870 0.1454 -0.2781
MDA-MB-231 Dasatinib
10
uM
LJP6
 2
I01
 72
hr
 1311 734 4961 0.1479 -0.2610
MDA-MB-231 Dasatinib
10
uM
LJP6
 3
I01
 72
hr
 1311 590 4973 0.1186 -0.3400
MDA-MB-231 Dasatinib
10
uM
LJP5
 1
D01
 72
hr
 1311 1115 5128 0.2174 -0.0793
MDA-MB-231 Dasatinib
10
uM
LJP5
 2
D01
 72
hr
 1311 1059 5100 0.2077 -0.1035
MDA-MB-231 Dasatinib
10
uM
LJP5
 3
D01
 72
hr
 1311 1067 5010 0.2129 -0.1013
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 1311 1397 5128 0.2724 0.0325
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 1311 1655 5100 0.3245 0.1260
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1311 1428 5010 0.2850 0.0449
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1311 1352 5128 0.2636 0.0155
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1311 1495 5100 0.2931 0.0690
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1311 1298 5010 0.2590 -0.0054
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 1311 1401 5128 0.2732 0.0340
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1311 1611 5100 0.3159 0.1106
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1311 1395 5010 0.2784 0.0323