LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 BI-2536
0.04
uM
LJP6
 1
D18
 72
hr
 1311 1230 4870 0.2526 -0.0334
MDA-MB-231 BI-2536
0.04
uM
LJP6
 2
D18
 72
hr
 1311 1452 4961 0.2927 0.0544
MDA-MB-231 BI-2536
0.04
uM
LJP6
 3
D18
 72
hr
 1311 1254 4973 0.2521 -0.0231
MDA-MB-231 BI-2536
0.12
uM
LJP6
 1
D17
 72
hr
 1311 1238 4870 0.2542 -0.0301
MDA-MB-231 BI-2536
0.12
uM
LJP6
 2
D17
 72
hr
 1311 1338 4961 0.2697 0.0104
MDA-MB-231 BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 1311 1260 4973 0.2533 -0.0207
MDA-MB-231 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 1311 1189 4870 0.2441 -0.0506
MDA-MB-231 BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 1311 1190 4961 0.2398 -0.0495
MDA-MB-231 BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 1311 1279 4973 0.2572 -0.0131
MDA-MB-231 BI-2536
1.11
uM
LJP6
 1
D15
 72
hr
 1311 1180 4870 0.2423 -0.0544
MDA-MB-231 BI-2536
1.11
uM
LJP6
 2
D15
 72
hr
 1311 1428 4961 0.2878 0.0452
MDA-MB-231 BI-2536
1.11
uM
LJP6
 3
D15
 72
hr
 1311 1221 4973 0.2455 -0.0366
MDA-MB-231 BI-2536
3.33
uM
LJP6
 1
D14
 72
hr
 1311 1193 4870 0.2450 -0.0489
MDA-MB-231 BI-2536
3.33
uM
LJP6
 2
D14
 72
hr
 1311 1457 4961 0.2937 0.0563
MDA-MB-231 BI-2536
3.33
uM
LJP6
 3
D14
 72
hr
 1311 1239 4973 0.2491 -0.0292
MDA-MB-231 BI-2536
10
uM
LJP6
 1
D13
 72
hr
 1311 1170 4870 0.2402 -0.0586
MDA-MB-231 BI-2536
10
uM
LJP6
 2
D13
 72
hr
 1311 1337 4961 0.2695 0.0100
MDA-MB-231 BI-2536
10
uM
LJP6
 3
D13
 72
hr
 1311 1230 4973 0.2473 -0.0329
MDA-MB-231 A443654
0.04
uM
LJP6
 1
I24
 72
hr
 1311 3931 4870 0.8072 0.7859
MDA-MB-231 A443654
0.04
uM
LJP6
 2
I24
 72
hr
 1311 4041 4961 0.8145 0.7972
MDA-MB-231 A443654
0.04
uM
LJP6
 3
I24
 72
hr
 1311 3746 4973 0.7532 0.7258
MDA-MB-231 A443654
0.12
uM
LJP6
 1
I23
 72
hr
 1311 3390 4870 0.6961 0.6515
MDA-MB-231 A443654
0.12
uM
LJP6
 2
I23
 72
hr
 1311 3306 4961 0.6663 0.6187
MDA-MB-231 A443654
0.12
uM
LJP6
 3
I23
 72
hr
 1311 3090 4973 0.6213 0.5614
MDA-MB-231 A443654
0.37
uM
LJP6
 1
I22
 72
hr
 1311 1851 4870 0.3801 0.1996