LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 NU7441
10
uM
LJP5
 2
C07
 72
hr
 1311 2407 5100 0.4720 0.3632
MDA-MB-231 NU7441
10
uM
LJP5
 3
C07
 72
hr
 1311 1992 5010 0.3975 0.2412
MDA-MB-231 OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 1311 4999 4870 1.0264 1.0278
MDA-MB-231 OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 1311 5302 4961 1.0686 1.0703
MDA-MB-231 OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 1311 5068 4973 1.0189 1.0196
MDA-MB-231 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1311 4314 4870 0.8858 0.8759
MDA-MB-231 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1311 4845 4961 0.9765 0.9754
MDA-MB-231 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1311 4345 4973 0.8736 0.8643
MDA-MB-231 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1311 3924 4870 0.8057 0.7843
MDA-MB-231 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1311 4472 4961 0.9013 0.8946
MDA-MB-231 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1311 3860 4973 0.7761 0.7530
MDA-MB-231 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1311 3586 4870 0.7363 0.7013
MDA-MB-231 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1311 4003 4961 0.8068 0.7884
MDA-MB-231 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1311 3607 4973 0.7252 0.6922
MDA-MB-231 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1311 3019 4870 0.6199 0.5534
MDA-MB-231 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1311 3383 4961 0.6818 0.6382
MDA-MB-231 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1311 3037 4973 0.6106 0.5474
MDA-MB-231 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1311 2125 4870 0.4363 0.2904
MDA-MB-231 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1311 2499 4961 0.5037 0.3991
MDA-MB-231 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1311 2139 4973 0.4301 0.2896
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1311 3164 4870 0.6497 0.5924
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1311 3150 4961 0.6349 0.5784
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1311 3071 4973 0.6174 0.5564
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1311 2553 4870 0.5242 0.4217
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1311 2274 4961 0.4583 0.3320