LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 1311 4874 4870 1.0008 1.0008
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 1311 5342 4961 1.0767 1.0785
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 1311 4777 4973 0.9604 0.9585
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 1311 4465 4870 0.9168 0.9103
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 1311 4895 4961 0.9866 0.9860
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 1311 4564 4973 0.9176 0.9125
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 1311 4609 4870 0.9464 0.9426
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1311 5207 4961 1.0495 1.0509
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 1311 4657 4973 0.9363 0.9327
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 1311 4970 4870 1.0205 1.0215
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 1311 5202 4961 1.0484 1.0499
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 1311 5070 4973 1.0193 1.0200
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 1311 4535 4870 0.9312 0.9260
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 1311 4888 4961 0.9852 0.9845
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 1311 4907 4973 0.9866 0.9860
MDA-MB-231 Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 1311 4163 4870 0.8548 0.8409
MDA-MB-231 Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 1311 4580 4961 0.9231 0.9183
MDA-MB-231 Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 1311 4560 4973 0.9168 0.9117
MDA-MB-231 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 1311 5195 5128 1.0130 1.0132
MDA-MB-231 CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 1311 5232 5100 1.0259 1.0263
MDA-MB-231 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 1311 5402 5010 1.0781 1.0793
MDA-MB-231 CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 1311 4984 5128 0.9719 0.9712
MDA-MB-231 CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 1311 5042 5100 0.9886 0.9884
MDA-MB-231 CP466722
0.12
uM
LJP5
 3
I11
 72
hr
 1311 5152 5010 1.0282 1.0289
MDA-MB-231 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 1311 5069 5128 0.9884 0.9882