LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 1235 4124 4326 0.9532 0.9477
MCF7 Brivanib
10
uM
LJP5
 1
P13
 72
hr
 1235 3241 4119 0.7868 0.7422
MCF7 Brivanib
10
uM
LJP5
 2
P13
 72
hr
 1235 3901 4356 0.8955 0.8822
MCF7 Brivanib
10
uM
LJP5
 3
P13
 72
hr
 1235 3774 4326 0.8723 0.8545
MCF7 CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 1235 3571 3974 0.8986 0.8770
MCF7 CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 1235 3437 4070 0.8444 0.8127
MCF7 CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 1235 3688 4126 0.8938 0.8750
MCF7 CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 1235 3453 3974 0.8689 0.8400
MCF7 CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 1235 3235 4070 0.7948 0.7500
MCF7 CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 1235 3033 4126 0.7350 0.6757
MCF7 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 1235 3187 3974 0.8019 0.7545
MCF7 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 1235 3205 4070 0.7874 0.7406
MCF7 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 1235 3301 4126 0.8000 0.7592
MCF7 CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 1235 2666 3974 0.6708 0.5782
MCF7 CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 1235 2481 4070 0.6095 0.4998
MCF7 CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 1235 2219 4126 0.5378 0.4002
MCF7 CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 1235 2657 3974 0.6686 0.5751
MCF7 CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 1235 2435 4070 0.5982 0.4836
MCF7 CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 1235 2387 4126 0.5785 0.4602
MCF7 CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 1235 1770 3974 0.4454 0.2378
MCF7 CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 1235 1372 4070 0.3371 0.0629
MCF7 CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 1235 1730 4126 0.4193 0.2135
MCF7 Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 1235 4831 3974 1.2156 1.2456
MCF7 Linifanib
0.04
uM
LJP6
 2
J12
 72
hr
 1235 4725 4070 1.1608 1.1811
MCF7 Linifanib
0.04
uM
LJP6
 3
J12
 72
hr
 1235 4806 4126 1.1647 1.1832