LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Trametinib
10
uM
LJP5
 2
P19
 72
hr
 1235 2540 4356 0.5831 0.4865
MCF7 Trametinib
10
uM
LJP5
 3
P19
 72
hr
 1235 2549 4326 0.5892 0.4927
MCF7 Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 1235 1441 3974 0.3626 0.0956
MCF7 Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 1235 1257 4070 0.3088 0.0101
MCF7 Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 1235 1389 4126 0.3366 0.0697
MCF7 Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 1235 1340 3974 0.3372 0.0494
MCF7 Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 1235 1359 4070 0.3339 0.0570
MCF7 Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 1235 1392 4126 0.3373 0.0710
MCF7 Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 1235 1355 3974 0.3410 0.0564
MCF7 Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 1235 1422 4070 0.3494 0.0852
MCF7 Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 1235 1413 4126 0.3424 0.0803
MCF7 Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 1235 1303 3974 0.3279 0.0321
MCF7 Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 1235 1225 4070 0.3010 -0.0049
MCF7 Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 1235 1056 4126 0.2559 -0.0862
MCF7 Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 1235 1123 3974 0.2826 -0.0550
MCF7 Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 1235 1035 4070 0.2543 -0.0978
MCF7 Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 1235 1003 4126 0.2431 -0.1129
MCF7 Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 1235 827 3974 0.2081 -0.2119
MCF7 Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 1235 853 4070 0.2096 -0.1937
MCF7 Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 1235 788 4126 0.1910 -0.2277
MCF7 Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 1235 3533 4119 0.8577 0.8309
MCF7 Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 1235 4064 4356 0.9329 0.9250
MCF7 Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 1235 4036 4326 0.9329 0.9246
MCF7 Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 1235 2628 4119 0.6380 0.5441
MCF7 Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 1235 2682 4356 0.6157 0.5317