LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GSK1059615 | 3.33 | uM | LJP6 | 2 | C02 | 72 | hr | 1235 | 1251 | 4070 | 0.3073 | 0.0073 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP6 | 3 | C02 | 72 | hr | 1235 | 1088 | 4126 | 0.2637 | -0.0704 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP5 | 1 | E02 | 72 | hr | 1235 | 1084 | 4119 | 0.2632 | -0.0725 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP5 | 2 | E02 | 72 | hr | 1235 | 1009 | 4356 | 0.2316 | -0.1054 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP5 | 3 | E02 | 72 | hr | 1235 | 1098 | 4326 | 0.2538 | -0.0631 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 1 | C01 | 72 | hr | 1235 | 689 | 3974 | 0.1734 | -0.2928 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 2 | C01 | 72 | hr | 1235 | 777 | 4070 | 0.1909 | -0.2363 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 3 | C01 | 72 | hr | 1235 | 706 | 4126 | 0.1711 | -0.2750 |
| MCF7 | GSK1059615 | 10 | uM | LJP5 | 1 | E01 | 72 | hr | 1235 | 792 | 4119 | 0.1923 | -0.2258 |
| MCF7 | GSK1059615 | 10 | uM | LJP5 | 2 | E01 | 72 | hr | 1235 | 751 | 4356 | 0.1724 | -0.2395 |
| MCF7 | GSK1059615 | 10 | uM | LJP5 | 3 | E01 | 72 | hr | 1235 | 763 | 4326 | 0.1764 | -0.2339 |
| MCF7 | Brivanib | 0.04 | uM | LJP5 | 1 | P18 | 72 | hr | 1235 | 3521 | 4119 | 0.8548 | 0.8273 |
| MCF7 | Brivanib | 0.04 | uM | LJP5 | 2 | P18 | 72 | hr | 1235 | 3428 | 4356 | 0.7869 | 0.7530 |
| MCF7 | Brivanib | 0.04 | uM | LJP5 | 3 | P18 | 72 | hr | 1235 | 3716 | 4326 | 0.8589 | 0.8387 |
| MCF7 | Brivanib | 0.12 | uM | LJP5 | 1 | P17 | 72 | hr | 1235 | 3460 | 4119 | 0.8400 | 0.8090 |
| MCF7 | Brivanib | 0.12 | uM | LJP5 | 2 | P17 | 72 | hr | 1235 | 3365 | 4356 | 0.7725 | 0.7352 |
| MCF7 | Brivanib | 0.12 | uM | LJP5 | 3 | P17 | 72 | hr | 1235 | 3683 | 4326 | 0.8513 | 0.8296 |
| MCF7 | Brivanib | 0.37 | uM | LJP5 | 1 | P16 | 72 | hr | 1235 | 3588 | 4119 | 0.8710 | 0.8472 |
| MCF7 | Brivanib | 0.37 | uM | LJP5 | 2 | P16 | 72 | hr | 1235 | 3663 | 4356 | 0.8409 | 0.8181 |
| MCF7 | Brivanib | 0.37 | uM | LJP5 | 3 | P16 | 72 | hr | 1235 | 3433 | 4326 | 0.7935 | 0.7599 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 1 | P15 | 72 | hr | 1235 | 3553 | 4119 | 0.8625 | 0.8368 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 2 | P15 | 72 | hr | 1235 | 3387 | 4356 | 0.7775 | 0.7415 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 3 | P15 | 72 | hr | 1235 | 4061 | 4326 | 0.9387 | 0.9312 |
| MCF7 | Brivanib | 3.33 | uM | LJP5 | 1 | P14 | 72 | hr | 1235 | 3565 | 4119 | 0.8655 | 0.8404 |
| MCF7 | Brivanib | 3.33 | uM | LJP5 | 2 | P14 | 72 | hr | 1235 | 4209 | 4356 | 0.9662 | 0.9625 |