LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 513 3950 10483 0.3768 0.5982
MCF 10A Linsitinib
1.11
uM
LJP5
 1
O21
 72
hr
 513 3868 10254 0.3772 0.5959
MCF 10A Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 513 3867 10349 0.3736 0.5936
MCF 10A Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 513 3850 10483 0.3672 0.5888
MCF 10A Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 513 3478 10254 0.3392 0.5572
MCF 10A Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 513 2882 10349 0.2785 0.4890
MCF 10A Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 513 2893 10483 0.2760 0.4878
MCF 10A Linsitinib
10
uM
LJP5
 1
O19
 72
hr
 513 1843 10254 0.1797 0.3443
MCF 10A Linsitinib
10
uM
LJP5
 2
O19
 72
hr
 513 2144 10349 0.2072 0.3908
MCF 10A Linsitinib
10
uM
LJP5
 3
O19
 72
hr
 513 2054 10483 0.1959 0.3752
MCF 10A Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 513 9619 10254 0.9380 0.9706
MCF 10A Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 513 9900 10349 0.9566 0.9796
MCF 10A Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 513 9788 10483 0.9337 0.9687
MCF 10A Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 513 9805 10254 0.9561 0.9793
MCF 10A Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 513 9841 10349 0.9509 0.9769
MCF 10A Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 513 10369 10483 0.9891 0.9950
MCF 10A Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 513 9488 10254 0.9252 0.9643
MCF 10A Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 513 9982 10349 0.9645 0.9834
MCF 10A Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 513 9358 10483 0.8926 0.9485
MCF 10A Ruxolitinib
1.11
uM
LJP5
 1
O15
 72
hr
 513 8719 10254 0.8502 0.9263
MCF 10A Ruxolitinib
1.11
uM
LJP5
 2
O15
 72
hr
 513 9365 10349 0.9049 0.9544
MCF 10A Ruxolitinib
1.11
uM
LJP5
 3
O15
 72
hr
 513 8796 10483 0.8390 0.9210
MCF 10A Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 513 8520 10254 0.8308 0.9160
MCF 10A Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 513 9383 10349 0.9066 0.9553
MCF 10A Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 513 8465 10483 0.8075 0.9041