LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 513 2415 10386 0.2325 0.4289
MCF 10A GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 513 2986 10494 0.2845 0.4985
MCF 10A GSK1904529A
0.12
uM
LJP6
 1
H23
 72
hr
 513 3211 10537 0.3047 0.5228
MCF 10A GSK1904529A
0.12
uM
LJP6
 2
H23
 72
hr
 513 2390 10386 0.2301 0.4255
MCF 10A GSK1904529A
0.12
uM
LJP6
 3
H23
 72
hr
 513 3549 10494 0.3382 0.5591
MCF 10A GSK1904529A
0.37
uM
LJP6
 1
H22
 72
hr
 513 2634 10537 0.2500 0.4552
MCF 10A GSK1904529A
0.37
uM
LJP6
 2
H22
 72
hr
 513 2311 10386 0.2225 0.4145
MCF 10A GSK1904529A
0.37
uM
LJP6
 3
H22
 72
hr
 513 2651 10494 0.2526 0.4581
MCF 10A GSK1904529A
1.11
uM
LJP6
 1
H21
 72
hr
 513 2321 10537 0.2203 0.4135
MCF 10A GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 513 1709 10386 0.1645 0.3194
MCF 10A GSK1904529A
1.11
uM
LJP6
 3
H21
 72
hr
 513 2057 10494 0.1960 0.3755
MCF 10A GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 513 2445 10537 0.2320 0.4305
MCF 10A GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 513 2220 10386 0.2137 0.4014
MCF 10A GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 513 1963 10494 0.1871 0.3608
MCF 10A GSK1904529A
10
uM
LJP6
 1
H19
 72
hr
 513 2872 10537 0.2725 0.4843
MCF 10A GSK1904529A
10
uM
LJP6
 2
H19
 72
hr
 513 2377 10386 0.2289 0.4237
MCF 10A GSK1904529A
10
uM
LJP6
 3
H19
 72
hr
 513 2804 10494 0.2672 0.4770
MCF 10A Linsitinib
0.04
uM
LJP5
 1
O24
 72
hr
 513 8424 10254 0.8215 0.9110
MCF 10A Linsitinib
0.04
uM
LJP5
 2
O24
 72
hr
 513 8109 10349 0.7835 0.8905
MCF 10A Linsitinib
0.04
uM
LJP5
 3
O24
 72
hr
 513 8511 10483 0.8118 0.9065
MCF 10A Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 513 7575 10254 0.7387 0.8646
MCF 10A Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 513 7174 10349 0.6932 0.8378
MCF 10A Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 513 6514 10483 0.6214 0.7929
MCF 10A Linsitinib
0.37
uM
LJP5
 1
O22
 72
hr
 513 4509 10254 0.4397 0.6536
MCF 10A Linsitinib
0.37
uM
LJP5
 2
O22
 72
hr
 513 4967 10349 0.4799 0.6883