LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 513 527 10537 0.0500 0.0060
MCF 10A SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 513 459 10386 0.0442 -0.0255
MCF 10A SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 513 478 10494 0.0455 -0.0163
MCF 10A SNS-032
10
uM
LJP6
 1
H13
 72
hr
 513 363 10537 0.0344 -0.0764
MCF 10A SNS-032
10
uM
LJP6
 2
H13
 72
hr
 513 374 10386 0.0360 -0.0704
MCF 10A SNS-032
10
uM
LJP6
 3
H13
 72
hr
 513 484 10494 0.0461 -0.0134
MCF 10A Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 513 381 10537 0.0362 -0.0661
MCF 10A Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 513 293 10386 0.0282 -0.1213
MCF 10A Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 513 380 10494 0.0362 -0.0668
MCF 10A Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 513 444 10537 0.0421 -0.0328
MCF 10A Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 513 370 10386 0.0356 -0.0727
MCF 10A Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 513 469 10494 0.0447 -0.0205
MCF 10A Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 513 501 10537 0.0475 -0.0056
MCF 10A Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 513 408 10386 0.0393 -0.0516
MCF 10A Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 513 553 10494 0.0527 0.0172
MCF 10A Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 513 583 10537 0.0553 0.0296
MCF 10A Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 513 614 10386 0.0591 0.0421
MCF 10A Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 513 569 10494 0.0542 0.0239
MCF 10A Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 513 489 10537 0.0464 -0.0111
MCF 10A Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 513 572 10386 0.0551 0.0252
MCF 10A Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 513 514 10494 0.0490 0.0003
MCF 10A Afatinib
10
uM
LJP6
 1
G19
 72
hr
 513 584 10537 0.0554 0.0300
MCF 10A Afatinib
10
uM
LJP6
 2
G19
 72
hr
 513 470 10386 0.0452 -0.0201
MCF 10A Afatinib
10
uM
LJP6
 3
G19
 72
hr
 513 631 10494 0.0601 0.0485
MCF 10A GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 513 3819 10537 0.3624 0.5846