LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A AZD8330
0.37
uM
LJP5
 1
G22
 72
hr
 513 498 10254 0.0486 -0.0070
MCF 10A AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 513 537 10349 0.0519 0.0104
MCF 10A AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 513 661 10483 0.0631 0.0598
MCF 10A AZD8330
1.11
uM
LJP5
 1
G21
 72
hr
 513 628 10254 0.0612 0.0478
MCF 10A AZD8330
1.11
uM
LJP5
 2
G21
 72
hr
 513 685 10349 0.0662 0.0688
MCF 10A AZD8330
1.11
uM
LJP5
 3
G21
 72
hr
 513 617 10483 0.0589 0.0432
MCF 10A AZD8330
3.33
uM
LJP5
 1
G20
 72
hr
 513 563 10254 0.0549 0.0216
MCF 10A AZD8330
3.33
uM
LJP5
 2
G20
 72
hr
 513 660 10349 0.0638 0.0597
MCF 10A AZD8330
3.33
uM
LJP5
 3
G20
 72
hr
 513 733 10483 0.0699 0.0853
MCF 10A AZD8330
10
uM
LJP5
 1
G19
 72
hr
 513 562 10254 0.0548 0.0212
MCF 10A AZD8330
10
uM
LJP5
 2
G19
 72
hr
 513 573 10349 0.0554 0.0257
MCF 10A AZD8330
10
uM
LJP5
 3
G19
 72
hr
 513 597 10483 0.0569 0.0353
MCF 10A TGX221
0.04
uM
LJP5
 1
H24
 72
hr
 513 8985 10254 0.8762 0.9397
MCF 10A TGX221
0.04
uM
LJP5
 2
H24
 72
hr
 513 9033 10349 0.8728 0.9382
MCF 10A TGX221
0.04
uM
LJP5
 3
H24
 72
hr
 513 8946 10483 0.8533 0.9284
MCF 10A TGX221
0.12
uM
LJP5
 1
H23
 72
hr
 513 8418 10254 0.8209 0.9107
MCF 10A TGX221
0.12
uM
LJP5
 2
H23
 72
hr
 513 9026 10349 0.8721 0.9378
MCF 10A TGX221
0.12
uM
LJP5
 3
H23
 72
hr
 513 9085 10483 0.8666 0.9353
MCF 10A TGX221
0.37
uM
LJP5
 1
H22
 72
hr
 513 8693 10254 0.8477 0.9250
MCF 10A TGX221
0.37
uM
LJP5
 2
H22
 72
hr
 513 9331 10349 0.9016 0.9528
MCF 10A TGX221
0.37
uM
LJP5
 3
H22
 72
hr
 513 9258 10483 0.8831 0.9437
MCF 10A TGX221
1.11
uM
LJP5
 1
H21
 72
hr
 513 8953 10254 0.8731 0.9381
MCF 10A TGX221
1.11
uM
LJP5
 2
H21
 72
hr
 513 8846 10349 0.8547 0.9289
MCF 10A TGX221
1.11
uM
LJP5
 3
H21
 72
hr
 513 8675 10483 0.8275 0.9148
MCF 10A TGX221
3.33
uM
LJP5
 1
H20
 72
hr
 513 1550 10254 0.1512 0.2915