LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 2 | J21 | 72 | hr | 513 | 3615 | 10349 | 0.3493 | 0.5690 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 3 | J21 | 72 | hr | 513 | 4181 | 10483 | 0.3988 | 0.6192 |
| MCF 10A | PF477736 | 3.33 | uM | LJP5 | 1 | J20 | 72 | hr | 513 | 874 | 10254 | 0.0852 | 0.1311 |
| MCF 10A | PF477736 | 3.33 | uM | LJP5 | 2 | J20 | 72 | hr | 513 | 1019 | 10349 | 0.0985 | 0.1714 |
| MCF 10A | PF477736 | 3.33 | uM | LJP5 | 3 | J20 | 72 | hr | 513 | 902 | 10483 | 0.0860 | 0.1383 |
| MCF 10A | PF477736 | 10 | uM | LJP5 | 1 | J19 | 72 | hr | 513 | 560 | 10254 | 0.0546 | 0.0203 |
| MCF 10A | PF477736 | 10 | uM | LJP5 | 2 | J19 | 72 | hr | 513 | 670 | 10349 | 0.0647 | 0.0634 |
| MCF 10A | PF477736 | 10 | uM | LJP5 | 3 | J19 | 72 | hr | 513 | 570 | 10483 | 0.0544 | 0.0243 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 1 | G06 | 72 | hr | 513 | 10442 | 10254 | 1.0183 | 1.0084 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 2 | G06 | 72 | hr | 513 | 11019 | 10349 | 1.0647 | 1.0291 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 3 | G06 | 72 | hr | 513 | 10404 | 10483 | 0.9924 | 0.9965 |
| MCF 10A | LDN-193189 | 0.12 | uM | LJP5 | 1 | G05 | 72 | hr | 513 | 9977 | 10254 | 0.9729 | 0.9873 |
| MCF 10A | LDN-193189 | 0.12 | uM | LJP5 | 2 | G05 | 72 | hr | 513 | 10033 | 10349 | 0.9694 | 0.9857 |
| MCF 10A | LDN-193189 | 0.12 | uM | LJP5 | 3 | G05 | 72 | hr | 513 | 9704 | 10483 | 0.9256 | 0.9648 |
| MCF 10A | LDN-193189 | 0.37 | uM | LJP5 | 1 | G04 | 72 | hr | 513 | 9369 | 10254 | 0.9136 | 0.9586 |
| MCF 10A | LDN-193189 | 0.37 | uM | LJP5 | 2 | G04 | 72 | hr | 513 | 9735 | 10349 | 0.9406 | 0.9720 |
| MCF 10A | LDN-193189 | 0.37 | uM | LJP5 | 3 | G04 | 72 | hr | 513 | 9858 | 10483 | 0.9403 | 0.9719 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 1 | G03 | 72 | hr | 513 | 8382 | 10254 | 0.8174 | 0.9088 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 2 | G03 | 72 | hr | 513 | 8634 | 10349 | 0.8342 | 0.9181 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 3 | G03 | 72 | hr | 513 | 8859 | 10483 | 0.8450 | 0.9241 |
| MCF 10A | LDN-193189 | 3.33 | uM | LJP5 | 1 | G02 | 72 | hr | 513 | 5345 | 10254 | 0.5212 | 0.7200 |
| MCF 10A | LDN-193189 | 3.33 | uM | LJP5 | 2 | G02 | 72 | hr | 513 | 6127 | 10349 | 0.5920 | 0.7721 |
| MCF 10A | LDN-193189 | 3.33 | uM | LJP5 | 3 | G02 | 72 | hr | 513 | 5606 | 10483 | 0.5347 | 0.7321 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 513 | 130 | 10254 | 0.0127 | -0.2723 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 513 | 153 | 10349 | 0.0148 | -0.2437 |