LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | LJP6 | 1 | J13 | 72 | hr | 1235 | 5294 | 3974 | 1.3321 | 1.3709 | |||
| MCF7 | LJP5 | 1 | J13 | 72 | hr | 1235 | 5461 | 4119 | 1.3257 | 1.3524 | |||
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 1 | D12 | 72 | hr | 1476 | 4380 | 3413 | 1.2832 | 1.4583 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1476 | 4824 | 3788 | 1.2733 | 1.3890 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 929 | 4101 | 3221 | 1.2730 | 1.2881 |
| BT-20 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1657 | 6819 | 5360 | 1.2722 | 1.3056 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 929 | 4036 | 3185 | 1.2671 | 1.2850 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1657 | 6985 | 5529 | 1.2632 | 1.2878 |
| BT-20 | Enzastaurin | 10 | uM | LJP5 | 3 | D13 | 72 | hr | 1657 | 6961 | 5529 | 1.2589 | 1.2833 |
| MCF7 | Gefitinib | 0.37 | uM | LJP6 | 1 | N10 | 72 | hr | 1235 | 4997 | 3974 | 1.2574 | 1.2911 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 3 | G06 | 72 | hr | 1235 | 5439 | 4326 | 1.2572 | 1.2698 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 1 | N16 | 72 | hr | 1235 | 4993 | 3974 | 1.2564 | 1.2900 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 1 | C15 | 72 | hr | 1476 | 4281 | 3413 | 1.2542 | 1.4122 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 1 | D11 | 72 | hr | 1476 | 4261 | 3413 | 1.2484 | 1.4029 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 929 | 4045 | 3243 | 1.2471 | 1.2605 |
| MCF7 | Linifanib | 0.37 | uM | LJP6 | 1 | J10 | 72 | hr | 1235 | 4946 | 3974 | 1.2445 | 1.2772 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1235 | 5374 | 4326 | 1.2421 | 1.2548 |
| SK-BR-3 | LJP5 | 2 | F11 | 72 | hr | 1476 | 4634 | 3731 | 1.2420 | 1.3518 | |||
| BT-20 | Enzastaurin | 10 | uM | LJP5 | 2 | D13 | 72 | hr | 1657 | 6961 | 5610 | 1.2406 | 1.2608 |
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 1235 | 4924 | 3974 | 1.2390 | 1.2711 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1476 | 4626 | 3734 | 1.2389 | 1.3471 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1476 | 4212 | 3413 | 1.2340 | 1.3800 |
| Hs 578T | Sorafenib | 0.37 | uM | LJP6 | 1 | B10 | 72 | hr | 929 | 3928 | 3185 | 1.2332 | 1.2504 |
| Hs 578T | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 929 | 3925 | 3185 | 1.2323 | 1.2494 |
| MCF7 | PIK-93 | 0.37 | uM | LJP5 | 3 | K16 | 72 | hr | 1235 | 5327 | 4326 | 1.2313 | 1.2439 |