LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 SB590885
0.12
uM
LJP5
 72
hr
 1209 4035 4093 0.9860 0.9801
MCF7 PIK-93
0.12
uM
LJP5
 72
hr
 1209 3784 4093 0.9246 0.8930
MCF7 KIN001-043
0.12
uM
LJP6
 72
hr
 1209 3261 4093 0.7967 0.7115
MCF7 Alpelisib
0.12
uM
LJP5
 72
hr
 1209 2769 4093 0.6765 0.5408
MCF7 Luminespib
0.12
uM
LJP5
 72
hr
 1209 1240 4093 0.3031 0.0108
MCF7 A443654
0.12
uM
LJP6
 72
hr
 1209 874 4093 0.2135 -0.1164
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1209 2358 4093 0.5763 0.3985
MCF7 XMD11-85h
0.12
uM
LJP6
 72
hr
 1209 3650 4093 0.8919 0.8466
MCF7 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1209 3908 4093 0.9548 0.9358
MCF7 WH-4-025
0.12
uM
LJP5
 72
hr
 1209 3456 4093 0.8445 0.7793
MCF7 WZ-4-145
0.12
uM
LJP6
 72
hr
 1209 2527 4093 0.6176 0.4571
MCF7 XMD16-144
0.12
uM
LJP5
 72
hr
 1209 1550 4093 0.3788 0.1182
MCF7 Brivanib
0.12
uM
LJP5
 72
hr
 1209 3892 4093 0.9509 0.9303
MCF7 Buparlisib
0.12
uM
LJP5
 72
hr
 1209 1881 4093 0.4596 0.2329
MCF7 BX-912
0.12
uM
LJP5
 72
hr
 1209 3549 4093 0.8673 0.8116
MCF7 Canertinib
0.12
uM
LJP6
 72
hr
 1209 3742 4093 0.9144 0.8785
MCF7 Celastrol
0.12
uM
LJP6
 72
hr
 1209 3933 4093 0.9609 0.9445
MCF7 CGP60474
0.12
uM
LJP5
 72
hr
 1209 668 4093 0.1634 -0.1876
MCF7 CGP60474
0.12
uM
LJP6
 72
hr
 1209 712 4093 0.1740 -0.1724
MCF7 CHIR-99021
0.12
uM
LJP6
 72
hr
 1209 3607 4093 0.8814 0.8317
MCF7 CP724714
0.12
uM
LJP5
 72
hr
 1209 3746 4093 0.9154 0.8799
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1209 4175 4093 1.0201 1.0286
MCF7 Crizotinib
0.12
uM
LJP5
 72
hr
 1209 3523 4093 0.8608 0.8024
MCF7 Momelotinib
0.12
uM
LJP5
 72
hr
 1209 3956 4093 0.9667 0.9527
MCF7 Dasatinib
0.12
uM
LJP5
 72
hr
 1209 2258 4093 0.5518 0.3637