LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A WZ3105
3.33
uM
LJP5
 72
hr
 962 211 10605 0.0199 -0.0779
MCF 10A XMD11-50
3.33
uM
LJP6
 72
hr
 962 2653 10605 0.2502 0.1753
MCF 10A Y39983
3.33
uM
LJP6
 72
hr
 962 8878 10605 0.8372 0.8209
MCF 10A YM 201636
3.33
uM
LJP5
 72
hr
 962 6073 10605 0.5727 0.5300
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 962 2212 10605 0.2086 0.1297
MCF 10A Afatinib
10.0
uM
LJP6
 72
hr
 962 1227 10605 0.1157 0.0275
MCF 10A Sigma A6730
10.0
uM
LJP5
 72
hr
 962 6093 10605 0.5746 0.5322
MCF 10A Alvocidib
10.0
uM
LJP6
 72
hr
 962 252 10605 0.0238 -0.0736
MCF 10A AT-7519
10.0
uM
LJP6
 72
hr
 962 195 10605 0.0184 -0.0795
MCF 10A AZD 5438
10.0
uM
LJP6
 72
hr
 962 333 10605 0.0314 -0.0652
MCF 10A AZD-6482
10.0
uM
LJP5
 72
hr
 962 4647 10605 0.4382 0.3821
MCF 10A AZD7762
10.0
uM
LJP6
 72
hr
 962 414 10605 0.0391 -0.0568
MCF 10A AZD8055
10.0
uM
LJP6
 72
hr
 962 57 10605 0.0054 -0.0939
MCF 10A AZD8330
10.0
uM
LJP5
 72
hr
 962 1760 10605 0.1660 0.0827
MCF 10A Barasertib
10.0
uM
LJP5
 72
hr
 962 1465 10605 0.1382 0.0522
MCF 10A BI-2536
10.0
uM
LJP6
 72
hr
 962 909 10605 0.0858 -0.0054
MCF 10A BMS345541
10.0
uM
LJP6
 72
hr
 962 8900 10605 0.8392 0.8232
MCF 10A SNS-032
10.0
uM
LJP6
 72
hr
 962 324 10605 0.0306 -0.0661
MCF 10A GDC-0980
10.0
uM
LJP5
 72
hr
 962 954 10605 0.0900 -0.0008
MCF 10A NVP-AEW541
10.0
uM
LJP5
 72
hr
 962 5417 10605 0.5108 0.4620
MCF 10A SB590885
10.0
uM
LJP5
 72
hr
 962 6137 10605 0.5787 0.5367
MCF 10A PIK-93
10.0
uM
LJP5
 72
hr
 962 4397 10605 0.4146 0.3562
MCF 10A KIN001-043
10.0
uM
LJP6
 72
hr
 962 4948 10605 0.4666 0.4134
MCF 10A Alpelisib
10.0
uM
LJP5
 72
hr
 962 4539 10605 0.4281 0.3710
MCF 10A Luminespib
10.0
uM
LJP5
 72
hr
 962 854 10605 0.0806 -0.0112