LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 TWS119
0.04
uM
LJP5
 72
hr
 1209 4199 4093 1.0259 1.0368
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1209 4065 4093 0.9933 0.9905
MCF7 Withaferin A
0.04
uM
LJP5
 72
hr
 1209 4135 4093 1.0103 1.0146
MCF7 Withaferin A
0.04
uM
LJP6
 72
hr
 1209 4048 4093 0.9891 0.9845
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1209 1334 4093 0.3259 0.0432
MCF7 WZ3105
0.04
uM
LJP5
 72
hr
 1209 572 4093 0.1398 -0.2211
MCF7 XMD11-50
0.04
uM
LJP6
 72
hr
 1209 3486 4093 0.8519 0.7897
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1209 4386 4093 1.0717 1.1018
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1209 4290 4093 1.0483 1.0686
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1209 2257 4093 0.5515 0.3634
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4093 0.8958 0.8520
MCF7 Sigma A6730
0.12
uM
LJP5
 72
hr
 1209 3269 4093 0.7988 0.7144
MCF7 Alvocidib
0.12
uM
LJP6
 72
hr
 1209 624 4093 0.1526 -0.2028
MCF7 AT-7519
0.12
uM
LJP6
 72
hr
 1209 653 4093 0.1595 -0.1930
MCF7 AZD 5438
0.12
uM
LJP6
 72
hr
 1209 1817 4093 0.4441 0.2109
MCF7 AZD-6482
0.12
uM
LJP5
 72
hr
 1209 4042 4093 0.9877 0.9825
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1209 1692 4093 0.4136 0.1676
MCF7 AZD8055
0.12
uM
LJP6
 72
hr
 1209 1108 4093 0.2709 -0.0350
MCF7 AZD8330
0.12
uM
LJP5
 72
hr
 1209 2154 4093 0.5264 0.3278
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1209 1458 4093 0.3563 0.0863
MCF7 BI-2536
0.12
uM
LJP6
 72
hr
 1209 1341 4093 0.3277 0.0457
MCF7 BMS345541
0.12
uM
LJP6
 72
hr
 1209 3947 4093 0.9643 0.9494
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1209 734 4093 0.1795 -0.1647
MCF7 GDC-0980
0.12
uM
LJP5
 72
hr
 1209 1002 4093 0.2450 -0.0718
MCF7 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1209 3114 4093 0.7609 0.6606