LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Dasatinib
0.37
uM
LJP6
 72
hr
 962 2012 10605 0.1897 0.1089
MCF 10A Dovitinib
0.37
uM
LJP5
 72
hr
 962 3910 10605 0.3687 0.3057
MCF 10A Enzastaurin
0.37
uM
LJP5
 72
hr
 962 10851 10605 1.0232 1.0255
MCF 10A Erlotinib
0.37
uM
LJP5
 72
hr
 962 2213 10605 0.2087 0.1298
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 962 8386 10605 0.7908 0.7699
MCF 10A R406
0.37
uM
LJP6
 72
hr
 962 9328 10605 0.8796 0.8676
MCF 10A Pictilisib
0.37
uM
LJP6
 72
hr
 962 7038 10605 0.6637 0.6302
MCF 10A Gefitinib
0.37
uM
LJP6
 72
hr
 962 2267 10605 0.2138 0.1354
MCF 10A Geldanamycin
0.37
uM
LJP5
 72
hr
 962 840 10605 0.0793 -0.0126
MCF 10A Geldanamycin
0.37
uM
LJP6
 72
hr
 962 706 10605 0.0666 -0.0265
MCF 10A GSK1059615
0.37
uM
LJP5
 72
hr
 962 5546 10605 0.5230 0.4754
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 962 7429 10605 0.7005 0.6706
MCF 10A GSK1904529A
0.37
uM
LJP6
 72
hr
 962 8562 10605 0.8074 0.7882
MCF 10A Omipalisib
0.37
uM
LJP6
 72
hr
 962 899 10605 0.0848 -0.0066
MCF 10A GSK 690693
0.37
uM
LJP5
 72
hr
 962 8775 10605 0.8274 0.8102
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 962 2477 10605 0.2336 0.1571
MCF 10A HG-5-113-01
0.37
uM
LJP5
 72
hr
 962 8630 10605 0.8138 0.7952
MCF 10A HG-5-88-01
0.37
uM
LJP6
 72
hr
 962 8600 10605 0.8110 0.7921
MCF 10A Imatinib
0.37
uM
LJP6
 72
hr
 962 10628 10605 1.0022 1.0024
MCF 10A JNK-9L
0.37
uM
LJP6
 72
hr
 962 5911 10605 0.5574 0.5132
MCF 10A JW-7-24-1
0.37
uM
LJP6
 72
hr
 962 9787 10605 0.9229 0.9152
MCF 10A Lapatinib
0.37
uM
LJP6
 72
hr
 962 10615 10605 1.0010 1.0011
MCF 10A LDN-193189
0.37
uM
LJP5
 72
hr
 962 9892 10605 0.9328 0.9261
MCF 10A Linifanib
0.37
uM
LJP6
 72
hr
 962 11407 10605 1.0756 1.0832
MCF 10A Linsitinib
0.37
uM
LJP5
 72
hr
 962 9986 10605 0.9416 0.9358