LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 962 6900 10605 0.6507 0.6158
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 962 8583 10605 0.8094 0.7903
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 962 2316 10605 0.2185 0.1405
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 962 11160 10605 1.0524 1.0576
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 962 9064 10605 0.8547 0.8402
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 962 380 10605 0.0359 -0.0603
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 962 460 10605 0.0434 -0.0520
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 962 7707 10605 0.7268 0.6995
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 962 1517 10605 0.1431 0.0576
MCF 10A Nilotinib
3.33
uM
LJP5
 72
hr
 962 9492 10605 0.8951 0.8846
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 962 10662 10605 1.0054 1.0059
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 962 8446 10605 0.7964 0.7761
MCF 10A Dactolisib
3.33
uM
LJP5
 72
hr
 962 1436 10605 0.1354 0.0491
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 962 4458 10605 0.4204 0.3626
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 962 4065 10605 0.3834 0.3218
MCF 10A PD0325901
3.33
uM
LJP5
 72
hr
 962 1867 10605 0.1761 0.0939
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 962 1133 10605 0.1069 0.0178
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 962 10254 10605 0.9669 0.9636
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 962 2663 10605 0.2511 0.1764
MCF 10A Pelitinib
3.33
uM
LJP5
 72
hr
 962 1435 10605 0.1353 0.0491
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 962 1103 10605 0.1040 0.0146
MCF 10A PF477736
3.33
uM
LJP5
 72
hr
 962 1786 10605 0.1685 0.0855
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 962 1254 10605 0.1182 0.0303
MCF 10A PHA-665752
3.33
uM
LJP5
 72
hr
 962 9974 10605 0.9406 0.9346
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 962 604 10605 0.0570 -0.0371