LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 962 976 10605 0.0921 0.0015
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 962 972 10605 0.0917 0.0011
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 962 9288 10605 0.8758 0.8634
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 962 1603 10605 0.1512 0.0665
MCF 10A Nilotinib
0.37
uM
LJP5
 72
hr
 962 9569 10605 0.9024 0.8926
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 962 10620 10605 1.0015 1.0016
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 962 10097 10605 0.9521 0.9473
MCF 10A Dactolisib
0.37
uM
LJP5
 72
hr
 962 1556 10605 0.1468 0.0616
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 962 7023 10605 0.6623 0.6286
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 962 5066 10605 0.4778 0.4257
MCF 10A PD0325901
0.37
uM
LJP5
 72
hr
 962 1826 10605 0.1722 0.0897
MCF 10A PD0325901
0.37
uM
LJP6
 72
hr
 962 1707 10605 0.1610 0.0773
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 962 10653 10605 1.0046 1.0050
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 962 3931 10605 0.3707 0.3080
MCF 10A Pelitinib
0.37
uM
LJP5
 72
hr
 962 1340 10605 0.1264 0.0392
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 962 1604 10605 0.1513 0.0666
MCF 10A PF477736
0.37
uM
LJP5
 72
hr
 962 7167 10605 0.6759 0.6435
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 962 5456 10605 0.5145 0.4660
MCF 10A PHA-665752
0.37
uM
LJP5
 72
hr
 962 10132 10605 0.9554 0.9510
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 962 1224 10605 0.1154 0.0272
MCF 10A PI103
0.37
uM
LJP6
 72
hr
 962 2433 10605 0.2295 0.1526
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 962 9239 10605 0.8712 0.8584
MCF 10A QL-X-138
0.37
uM
LJP6
 72
hr
 962 9230 10605 0.8704 0.8574
MCF 10A QL-XII-47
0.37
uM
LJP6
 72
hr
 962 8582 10605 0.8093 0.7903
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 962 2901 10605 0.2736 0.2011