LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Gefitinib
0.04
uM
LJP6
 72
hr
 1657 5762 5505 1.0466 1.0667
BT-20 Linifanib
0.12
uM
LJP6
 72
hr
 1657 5763 5505 1.0469 1.0670
SK-BR-3 WH-4-025
0.04
uM
LJP5
 72
hr
 1476 3842 3694 1.0402 1.0670
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 72
hr
 868 3662 3486 1.0505 1.0672
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4352 4156 1.0472 1.0672
BT-20 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1657 5765 5505 1.0471 1.0674
BT-20 PD184352
0.04
uM
LJP5
 72
hr
 1657 5766 5505 1.0473 1.0677
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 868 3667 3486 1.0518 1.0690
Hs 578T YM 201636
0.04
uM
LJP5
 72
hr
 929 3387 3228 1.0492 1.0691
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 72
hr
 868 3668 3486 1.0522 1.0695
MDA-MB-231 XL147
0.12
uM
LJP5
 72
hr
 868 3671 3486 1.0531 1.0708
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 929 3393 3228 1.0511 1.0717
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 513 11110 10401 1.0682 1.0717
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 513 11112 10401 1.0684 1.0720
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 929 3394 3228 1.0514 1.0722
MCF7 SB590885
0.12
uM
LJP5
 72
hr
 1235 4368 4156 1.0510 1.0726
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 513 11127 10401 1.0698 1.0734
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 513 11131 10401 1.0702 1.0738
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 513 11133 10401 1.0704 1.0741
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 868 3680 3486 1.0557 1.0742
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 72
hr
 868 3684 3486 1.0567 1.0755
Hs 578T CP466722
1.11
uM
LJP5
 72
hr
 929 3402 3228 1.0539 1.0757
MDA-MB-231 CP466722
0.12
uM
LJP5
 72
hr
 868 3685 3486 1.0570 1.0759
BT-20 PD184352
0.12
uM
LJP5
 72
hr
 1657 5799 5505 1.0534 1.0764
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 868 3686 3486 1.0573 1.0764