LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Dovitinib
3.33
uM
LJP5
 72
hr
 1657 2475 5505 0.4495 0.2124
BT-20 Enzastaurin
3.33
uM
LJP5
 72
hr
 1657 6589 5505 1.1969 1.2817
BT-20 Erlotinib
3.33
uM
LJP5
 72
hr
 1657 4827 5505 0.8768 0.8237
BT-20 Foretinib
3.33
uM
LJP5
 72
hr
 1657 1624 5505 0.2950 -0.0087
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 929 3089 3228 0.9569 0.9395
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 929 2959 3228 0.9169 0.8833
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 929 1386 3228 0.4294 0.1987
BT-20 Geldanamycin
3.33
uM
LJP5
 72
hr
 1657 1735 5505 0.3153 0.0203
BT-20 WH-4-025
0.37
uM
LJP5
 72
hr
 1657 3593 5505 0.6527 0.5031
BT-20 GSK1059615
3.33
uM
LJP5
 72
hr
 1657 968 5505 0.1758 -0.1793
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1657 5376 5505 0.9765 0.9663
BT-20 Sigma A6730
0.04
uM
LJP5
 72
hr
 1657 4910 5505 0.8918 0.8452
BT-20 XMD16-144
0.37
uM
LJP5
 72
hr
 1657 2144 5505 0.3894 0.1264
BT-20 GSK 690693
3.33
uM
LJP5
 72
hr
 1657 3450 5505 0.6266 0.4658
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1657 5313 5505 0.9651 0.9501
BT-20 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1657 2727 5505 0.4954 0.2781
BT-20 Buparlisib
0.37
uM
LJP5
 72
hr
 1657 3669 5505 0.6665 0.5229
BT-20 NU7441
3.33
uM
LJP5
 72
hr
 1657 5366 5505 0.9747 0.9638
BT-20 BX-912
0.37
uM
LJP5
 72
hr
 1657 5456 5505 0.9910 0.9872
BT-20 Linsitinib
0.04
uM
LJP5
 72
hr
 1657 4776 5505 0.8676 0.8106
BT-20 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1657 5821 5505 1.0573 1.0820
BT-20 LDN-193189
3.33
uM
LJP5
 72
hr
 1657 2144 5505 0.3895 0.1265
BT-20 SB590885
0.12
uM
LJP5
 72
hr
 1657 5393 5505 0.9795 0.9707
BT-20 Linsitinib
3.33
uM
LJP5
 72
hr
 1657 4834 5505 0.8781 0.8255
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 929 1571 3228 0.4868 0.2793