LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10835 | 10401 | 1.0417 | 1.0439 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10826 | 10401 | 1.0408 | 1.0430 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10774 | 10401 | 1.0358 | 1.0377 |
| MCF 10A | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10725 | 10401 | 1.0312 | 1.0328 |
| MCF 10A | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 513 | 10721 | 10401 | 1.0308 | 1.0323 |
| MCF 10A | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10715 | 10401 | 1.0302 | 1.0317 |
| MCF 10A | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10714 | 10401 | 1.0301 | 1.0316 |
| MCF 10A | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10711 | 10401 | 1.0298 | 1.0314 |
| MCF 10A | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10700 | 10401 | 1.0288 | 1.0303 |
| MCF 10A | XL147 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10693 | 10401 | 1.0281 | 1.0296 |
| MCF 10A | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 513 | 10692 | 10401 | 1.0280 | 1.0294 |
| MCF 10A | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10673 | 10401 | 1.0261 | 1.0275 |
| MCF 10A | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10627 | 10401 | 1.0217 | 1.0228 |
| MCF 10A | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10621 | 10401 | 1.0212 | 1.0223 |
| MCF 10A | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 10609 | 10401 | 1.0200 | 1.0210 |
| MCF 10A | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10600 | 10401 | 1.0192 | 1.0202 |
| MCF 10A | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10587 | 10401 | 1.0179 | 1.0188 |
| MCF 10A | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10571 | 10401 | 1.0163 | 1.0172 |
| MCF 10A | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 513 | 10543 | 10401 | 1.0137 | 1.0144 |
| MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 513 | 10535 | 10401 | 1.0129 | 1.0136 |
| MCF 10A | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 513 | 10522 | 10401 | 1.0117 | 1.0123 |
| MCF 10A | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 513 | 10502 | 10401 | 1.0098 | 1.0103 |
| MCF 10A | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 513 | 10484 | 10401 | 1.0080 | 1.0084 |
| MCF 10A | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10462 | 10401 | 1.0059 | 1.0062 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10459 | 10401 | 1.0056 | 1.0059 |