LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 513 | 11759 | 10401 | 1.1306 | 1.1374 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 513 | 11587 | 10401 | 1.1140 | 1.1199 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 513 | 11579 | 10401 | 1.1132 | 1.1191 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 513 | 11575 | 10401 | 1.1129 | 1.1188 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 513 | 11521 | 10401 | 1.1077 | 1.1133 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 513 | 11182 | 10401 | 1.0751 | 1.0790 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 11133 | 10401 | 1.0704 | 1.0741 |
| MCF 10A | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 513 | 11131 | 10401 | 1.0702 | 1.0738 |
| MCF 10A | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 513 | 11127 | 10401 | 1.0698 | 1.0734 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 513 | 11112 | 10401 | 1.0684 | 1.0720 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 513 | 11110 | 10401 | 1.0682 | 1.0717 |
| MCF 10A | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 513 | 11029 | 10401 | 1.0604 | 1.0635 |
| MCF 10A | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10983 | 10401 | 1.0560 | 1.0589 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 513 | 10979 | 10401 | 1.0556 | 1.0585 |
| MCF 10A | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10965 | 10401 | 1.0543 | 1.0571 |
| MCF 10A | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10964 | 10401 | 1.0541 | 1.0570 |
| MCF 10A | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 10927 | 10401 | 1.0506 | 1.0533 |
| MCF 10A | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 513 | 10923 | 10401 | 1.0502 | 1.0528 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10904 | 10401 | 1.0483 | 1.0509 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10898 | 10401 | 1.0478 | 1.0502 |
| MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10896 | 10401 | 1.0476 | 1.0501 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10892 | 10401 | 1.0472 | 1.0497 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 10885 | 10401 | 1.0465 | 1.0489 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 513 | 10876 | 10401 | 1.0457 | 1.0481 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10852 | 10401 | 1.0433 | 1.0456 |