LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A LDN-193189
10.0
uM
LJP5
72
hr
513 132 10401 0.0127 -0.0385
MCF 10A Dasatinib
10.0
uM
LJP6
72
hr
513 217 10401 0.0209 -0.0300
MCF 10A Canertinib
10.0
uM
LJP6
72
hr
513 223 10401 0.0215 -0.0293
MCF 10A HG-6-64-01
10.0
uM
LJP6
72
hr
513 246 10401 0.0237 -0.0270
MCF 10A Geldanamycin
10.0
uM
LJP6
72
hr
513 262 10401 0.0252 -0.0254
MCF 10A GSK1059615
10.0
uM
LJP5
72
hr
513 283 10401 0.0272 -0.0233
MCF 10A Dasatinib
3.33
uM
LJP6
72
hr
513 305 10401 0.0293 -0.0211
MCF 10A Geldanamycin
10.0
uM
LJP5
72
hr
513 307 10401 0.0296 -0.0208
MCF 10A GSK1059615
10.0
uM
LJP6
72
hr
513 317 10401 0.0305 -0.0199
MCF 10A Withaferin A
10.0
uM
LJP5
72
hr
513 321 10401 0.0309 -0.0194
MCF 10A Withaferin A
10.0
uM
LJP6
72
hr
513 325 10401 0.0312 -0.0191
MCF 10A Buparlisib
10.0
uM
LJP5
72
hr
513 331 10401 0.0319 -0.0184
MCF 10A Dasatinib
10.0
uM
LJP5
72
hr
513 332 10401 0.0320 -0.0183
MCF 10A Dasatinib
3.33
uM
LJP5
72
hr
513 337 10401 0.0324 -0.0178
MCF 10A Withaferin A
3.33
uM
LJP6
72
hr
513 345 10401 0.0332 -0.0170
MCF 10A Radicicol
10.0
uM
LJP5
72
hr
513 347 10401 0.0334 -0.0168
MCF 10A GSK1059615
3.33
uM
LJP5
72
hr
513 348 10401 0.0335 -0.0167
MCF 10A A443654
3.33
uM
LJP6
72
hr
513 351 10401 0.0338 -0.0164
MCF 10A Afatinib
0.04
uM
LJP6
72
hr
513 351 10401 0.0338 -0.0164
MCF 10A AZD7762
10.0
uM
LJP6
72
hr
513 353 10401 0.0340 -0.0162
MCF 10A QL-X-138
10.0
uM
LJP6
72
hr
513 363 10401 0.0349 -0.0152
MCF 10A Mitoxantrone
3.33
uM
LJP5
72
hr
513 371 10401 0.0357 -0.0144
MCF 10A Withaferin A
3.33
uM
LJP5
72
hr
513 374 10401 0.0360 -0.0140
MCF 10A TWS119
10.0
uM
LJP5
72
hr
513 385 10401 0.0371 -0.0129
MCF 10A Buparlisib
3.33
uM
LJP5
72
hr
513 386 10401 0.0371 -0.0129
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