LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A R406
0.04
uM
LJP6
 72
hr
 513 9273 10401 0.8915 0.8859
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 513 5147 10401 0.4949 0.4687
MCF 10A Gefitinib
0.04
uM
LJP6
 72
hr
 513 7067 10401 0.6795 0.6628
MCF 10A Geldanamycin
0.04
uM
LJP5
 72
hr
 513 607 10401 0.0584 0.0095
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 513 641 10401 0.0616 0.0129
MCF 10A GSK1059615
0.04
uM
LJP5
 72
hr
 513 10000 10401 0.9615 0.9595
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 513 8625 10401 0.8293 0.8204
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 513 3073 10401 0.2955 0.2589
MCF 10A Omipalisib
0.04
uM
LJP6
 72
hr
 513 714 10401 0.0687 0.0203
MCF 10A GSK 690693
0.04
uM
LJP5
 72
hr
 513 9415 10401 0.9052 0.9003
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 513 9055 10401 0.8706 0.8639
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 513 9757 10401 0.9381 0.9349
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 513 7496 10401 0.7207 0.7062
MCF 10A Imatinib
0.04
uM
LJP6
 72
hr
 513 10714 10401 1.0301 1.0316
MCF 10A JNK-9L
0.04
uM
LJP6
 72
hr
 513 9018 10401 0.8671 0.8602
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 513 9324 10401 0.8965 0.8911
MCF 10A Lapatinib
0.04
uM
LJP6
 72
hr
 513 9294 10401 0.8936 0.8881
MCF 10A LDN-193189
0.04
uM
LJP5
 72
hr
 513 10621 10401 1.0212 1.0223
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 513 11575 10401 1.1129 1.1188
MCF 10A Linsitinib
0.04
uM
LJP5
 72
hr
 513 8348 10401 0.8026 0.7924
MCF 10A Mitoxantrone
0.04
uM
LJP5
 72
hr
 513 1036 10401 0.0996 0.0529
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 513 907 10401 0.0873 0.0399
MCF 10A MK2206
0.04
uM
LJP6
 72
hr
 513 10448 10401 1.0045 1.0048
MCF 10A Neratinib
0.04
uM
LJP5
 72
hr
 513 1007 10401 0.0968 0.0499
MCF 10A Nilotinib
0.04
uM
LJP5
 72
hr
 513 10927 10401 1.0506 1.0533