LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 513 10876 10401 1.0457 1.0481
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 513 10965 10401 1.0543 1.0571
MCF 10A Dactolisib
0.04
uM
LJP5
 72
hr
 513 1969 10401 0.1893 0.1472
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 513 6950 10401 0.6682 0.6510
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 513 7760 10401 0.7461 0.7329
MCF 10A PD0325901
0.04
uM
LJP5
 72
hr
 513 1058 10401 0.1017 0.0551
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 513 1025 10401 0.0986 0.0518
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 513 10923 10401 1.0502 1.0528
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 513 4620 10401 0.4442 0.4154
MCF 10A Pelitinib
0.04
uM
LJP5
 72
hr
 513 2132 10401 0.2050 0.1638
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 513 6160 10401 0.5923 0.5711
MCF 10A PF477736
0.04
uM
LJP5
 72
hr
 513 9417 10401 0.9054 0.9005
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 513 8702 10401 0.8367 0.8282
MCF 10A PHA-665752
0.04
uM
LJP5
 72
hr
 513 9929 10401 0.9546 0.9523
MCF 10A PHA-793887
0.04
uM
LJP6
 72
hr
 513 1245 10401 0.1198 0.0741
MCF 10A PI103
0.04
uM
LJP6
 72
hr
 513 8242 10401 0.7925 0.7817
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 513 10627 10401 1.0217 1.0228
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 513 9244 10401 0.8888 0.8830
MCF 10A QL-XII-47
0.04
uM
LJP6
 72
hr
 513 9369 10401 0.9008 0.8956
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 513 6621 10401 0.6366 0.6177
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 513 6388 10401 0.6142 0.5941
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 513 10313 10401 0.9916 0.9911
MCF 10A Ruxolitinib
0.04
uM
LJP5
 72
hr
 513 9769 10401 0.9392 0.9361
MCF 10A XL147
0.04
uM
LJP5
 72
hr
 513 10693 10401 1.0281 1.0296
MCF 10A Saracatinib
0.04
uM
LJP6
 72
hr
 513 10896 10401 1.0476 1.0501