LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
10.0
uM
LJP6
 72
hr
 868 456 3486 0.1308 -0.1574
MDA-MB-231 Dovitinib
10.0
uM
LJP5
 72
hr
 868 1494 3486 0.4287 0.2393
MDA-MB-231 Enzastaurin
10.0
uM
LJP5
 72
hr
 868 3263 3486 0.9361 0.9149
MDA-MB-231 Erlotinib
10.0
uM
LJP5
 72
hr
 868 2108 3486 0.6046 0.4736
MDA-MB-231 Foretinib
10.0
uM
LJP5
 72
hr
 868 635 3486 0.1822 -0.0889
MDA-MB-231 R406
10.0
uM
LJP6
 72
hr
 868 1692 3486 0.4854 0.3148
MDA-MB-231 Pictilisib
10.0
uM
LJP6
 72
hr
 868 1806 3486 0.5181 0.3583
MDA-MB-231 Gefitinib
10.0
uM
LJP6
 72
hr
 868 3151 3486 0.9038 0.8719
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 72
hr
 868 603 3486 0.1731 -0.1011
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 72
hr
 868 555 3486 0.1592 -0.1196
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 72
hr
 868 586 3486 0.1682 -0.1076
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 72
hr
 868 660 3486 0.1894 -0.0794
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 72
hr
 868 3375 3486 0.9682 0.9577
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 72
hr
 868 1031 3486 0.2957 0.0622
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 72
hr
 868 3140 3486 0.9007 0.8678
MDA-MB-231 GW843682X
10.0
uM
LJP6
 72
hr
 868 1218 3486 0.3494 0.1336
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 72
hr
 868 948 3486 0.2721 0.0308
MDA-MB-231 HG-5-88-01
10.0
uM
LJP6
 72
hr
 868 1605 3486 0.4605 0.2816
MDA-MB-231 Imatinib
10.0
uM
LJP6
 72
hr
 868 3233 3486 0.9274 0.9034
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 72
hr
 868 831 3486 0.2384 -0.0142
MDA-MB-231 JW-7-24-1
10.0
uM
LJP6
 72
hr
 868 876 3486 0.2515 0.0033
MDA-MB-231 Lapatinib
10.0
uM
LJP6
 72
hr
 868 2607 3486 0.7479 0.6643
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 72
hr
 868 332 3486 0.0952 -0.2048
MDA-MB-231 Linifanib
10.0
uM
LJP6
 72
hr
 868 1371 3486 0.3933 0.1922
MDA-MB-231 Linsitinib
10.0
uM
LJP5
 72
hr
 868 2212 3486 0.6345 0.5133