LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Selumetinib
1.11
uM
LJP6
 72
hr
 868 1812 3486 0.5199 0.3608
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 868 2714 3486 0.7786 0.7051
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 72
hr
 868 2640 3486 0.7572 0.6767
MDA-MB-231 SU11274
1.11
uM
LJP5
 72
hr
 868 3394 3486 0.9735 0.9647
MDA-MB-231 Fedratinib
1.11
uM
LJP5
 72
hr
 868 2260 3486 0.6483 0.5317
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 868 2919 3486 0.8373 0.7833
MDA-MB-231 Torin1
1.11
uM
LJP6
 72
hr
 868 1323 3486 0.3795 0.1737
MDA-MB-231 Torin2
1.11
uM
LJP5
 72
hr
 868 1038 3486 0.2977 0.0649
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 868 1078 3486 0.3093 0.0803
MDA-MB-231 Trametinib
1.11
uM
LJP5
 72
hr
 868 1147 3486 0.3290 0.1065
MDA-MB-231 TWS119
1.11
uM
LJP5
 72
hr
 868 2921 3486 0.8378 0.7841
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 72
hr
 868 2853 3486 0.8183 0.7581
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 868 936 3486 0.2687 0.0262
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 868 807 3486 0.2317 -0.0231
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 72
hr
 868 1776 3486 0.5096 0.3470
MDA-MB-231 WZ3105
1.11
uM
LJP5
 72
hr
 868 722 3486 0.2071 -0.0558
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 72
hr
 868 1436 3486 0.4119 0.2169
MDA-MB-231 Y39983
1.11
uM
LJP6
 72
hr
 868 2552 3486 0.7322 0.6434
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 868 2841 3486 0.8151 0.7538
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 72
hr
 868 2454 3486 0.7040 0.6058
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 868 2182 3486 0.6260 0.5019
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 868 2960 3486 0.8490 0.7990
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 72
hr
 868 612 3486 0.1755 -0.0978
MDA-MB-231 AT-7519
3.33
uM
LJP6
 72
hr
 868 588 3486 0.1689 -0.1067
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 72
hr
 868 793 3486 0.2277 -0.0284