LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 868 | 3044 | 3486 | 0.8733 | 0.8313 |
| MDA-MB-231 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2642 | 3486 | 0.7580 | 0.6778 |
| MDA-MB-231 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 868 | 1539 | 3486 | 0.4414 | 0.2562 |
| MDA-MB-231 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1817 | 3486 | 0.5212 | 0.3624 |
| MDA-MB-231 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 868 | 1681 | 3486 | 0.4823 | 0.3106 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 868 | 1235 | 3486 | 0.3543 | 0.1403 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1020 | 3486 | 0.2926 | 0.0580 |
| MDA-MB-231 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 868 | 3645 | 3486 | 1.0455 | 1.0606 |
| MDA-MB-231 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2132 | 3486 | 0.6116 | 0.4828 |
| MDA-MB-231 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 868 | 2723 | 3486 | 0.7812 | 0.7087 |
| MDA-MB-231 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 868 | 1645 | 3486 | 0.4718 | 0.2967 |
| MDA-MB-231 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 868 | 1921 | 3486 | 0.5510 | 0.4021 |
| MDA-MB-231 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2382 | 3486 | 0.6834 | 0.5785 |
| MDA-MB-231 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 868 | 3577 | 3486 | 1.0261 | 1.0347 |
| MDA-MB-231 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 868 | 914 | 3486 | 0.2624 | 0.0178 |
| MDA-MB-231 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1950 | 3486 | 0.5593 | 0.4132 |
| MDA-MB-231 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 868 | 3032 | 3486 | 0.8699 | 0.8267 |
| MDA-MB-231 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2483 | 3486 | 0.7124 | 0.6170 |
| MDA-MB-231 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1018 | 3486 | 0.2920 | 0.0572 |
| MDA-MB-231 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 868 | 1146 | 3486 | 0.3287 | 0.1061 |
| MDA-MB-231 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 868 | 1277 | 3486 | 0.3664 | 0.1563 |
| MDA-MB-231 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 868 | 2926 | 3486 | 0.8393 | 0.7860 |
| MDA-MB-231 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 868 | 3326 | 3486 | 0.9540 | 0.9387 |
| MDA-MB-231 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 868 | 3805 | 3486 | 1.0915 | 1.1218 |
| MDA-MB-231 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 868 | 2114 | 3486 | 0.6065 | 0.4760 |