LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1371 | 3694 | 0.3713 | -0.0474 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2787 | 3694 | 0.7545 | 0.5909 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1630 | 3694 | 0.4413 | 0.0691 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3146 | 3694 | 0.8516 | 0.7528 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3484 | 3694 | 0.9431 | 0.9053 |
| SK-BR-3 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3778 | 3694 | 1.0228 | 1.0380 |
| SK-BR-3 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1505 | 3694 | 0.4074 | 0.0128 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1566 | 3694 | 0.4239 | 0.0403 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2449 | 3694 | 0.6631 | 0.4386 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1428 | 3694 | 0.3867 | -0.0218 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1485 | 3694 | 0.4021 | 0.0039 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3872 | 3694 | 1.0482 | 1.0803 |
| SK-BR-3 | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1988 | 3694 | 0.5383 | 0.2307 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1768 | 3694 | 0.4786 | 0.1314 |
| SK-BR-3 | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4233 | 3694 | 1.1461 | 1.2434 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4098 | 3694 | 1.1094 | 1.1822 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4081 | 3694 | 1.1048 | 1.1747 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3706 | 3694 | 1.0034 | 1.0057 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3411 | 3694 | 0.9235 | 0.8725 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1618 | 3694 | 0.4381 | 0.0639 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1173 | 3694 | 0.3176 | -0.1368 |
| SK-BR-3 | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3274 | 3694 | 0.8863 | 0.8106 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2628 | 3694 | 0.7115 | 0.5194 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4118 | 3694 | 1.1148 | 1.1912 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3842 | 3694 | 1.0402 | 1.0670 |