LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 868 2935 3486 0.8418 0.7894
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 72
hr
 868 1291 3486 0.3705 0.1618
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 868 2804 3486 0.8045 0.7396
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 72
hr
 868 3425 3486 0.9826 0.9768
MDA-MB-231 BX-912
0.12
uM
LJP5
 72
hr
 868 3172 3486 0.9099 0.8801
MDA-MB-231 Canertinib
0.12
uM
LJP6
 72
hr
 868 3383 3486 0.9705 0.9608
MDA-MB-231 Celastrol
0.12
uM
LJP6
 72
hr
 868 3735 3486 1.0714 1.0951
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 868 946 3486 0.2714 0.0299
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 868 830 3486 0.2381 -0.0146
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 868 2799 3486 0.8029 0.7376
MDA-MB-231 CP724714
0.12
uM
LJP5
 72
hr
 868 2625 3486 0.7531 0.6713
MDA-MB-231 CP466722
0.12
uM
LJP5
 72
hr
 868 3685 3486 1.0570 1.0759
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 72
hr
 868 2779 3486 0.7971 0.7298
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 72
hr
 868 2674 3486 0.7672 0.6900
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 72
hr
 868 736 3486 0.2113 -0.0502
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 72
hr
 868 581 3486 0.1668 -0.1094
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 72
hr
 868 2408 3486 0.6907 0.5881
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 72
hr
 868 3419 3486 0.9807 0.9743
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 72
hr
 868 3174 3486 0.9105 0.8808
MDA-MB-231 Foretinib
0.12
uM
LJP5
 72
hr
 868 2270 3486 0.6511 0.5354
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 868 3202 3486 0.9184 0.8914
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 72
hr
 868 2611 3486 0.7491 0.6659
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 72
hr
 868 3934 3486 1.1284 1.1710
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 72
hr
 868 1081 3486 0.3103 0.0816
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 72
hr
 868 1227 3486 0.3519 0.1371