LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 868 2948 3486 0.8457 0.7945
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 868 2747 3486 0.7879 0.7176
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 868 635 3486 0.1823 -0.0888
MDA-MB-231 AT-7519
0.12
uM
LJP6
 72
hr
 868 2196 3486 0.6299 0.5072
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 72
hr
 868 2534 3486 0.7269 0.6364
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 72
hr
 868 3065 3486 0.8791 0.8391
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 868 1608 3486 0.4613 0.2827
MDA-MB-231 AZD8055
0.12
uM
LJP6
 72
hr
 868 1409 3486 0.4043 0.2068
MDA-MB-231 AZD8330
0.12
uM
LJP5
 72
hr
 868 981 3486 0.2816 0.0434
MDA-MB-231 Barasertib
0.12
uM
LJP5
 72
hr
 868 1279 3486 0.3669 0.1569
MDA-MB-231 BI-2536
0.12
uM
LJP6
 72
hr
 868 1099 3486 0.3154 0.0884
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 868 3667 3486 1.0518 1.0690
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 868 821 3486 0.2355 -0.0180
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 72
hr
 868 2220 3486 0.6368 0.5163
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 72
hr
 868 3503 3486 1.0050 1.0066
MDA-MB-231 SB590885
0.12
uM
LJP5
 72
hr
 868 3269 3486 0.9378 0.9172
MDA-MB-231 PIK-93
0.12
uM
LJP5
 72
hr
 868 3631 3486 1.0415 1.0552
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 868 3249 3486 0.9321 0.9096
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 72
hr
 868 3390 3486 0.9724 0.9632
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 868 1017 3486 0.2917 0.0569
MDA-MB-231 A443654
0.12
uM
LJP6
 72
hr
 868 1018 3486 0.2920 0.0572
MDA-MB-231 OSI-027
0.12
uM
LJP6
 72
hr
 868 3222 3486 0.9242 0.8990
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 72
hr
 868 2892 3486 0.8295 0.7730
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 72
hr
 868 3636 3486 1.0430 1.0573
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 868 1629 3486 0.4674 0.2909