LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 3 | L15 | 72 | hr | 1401 | 2729 | 4223 | 0.6462 | 0.4705 |
SK-BR-3 | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 1401 | 4078 | 4223 | 0.9656 | 0.9486 |
SK-BR-3 | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 1401 | 3919 | 4223 | 0.9280 | 0.8922 |
SK-BR-3 | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 1401 | 4325 | 4223 | 1.0241 | 1.0361 |
SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1401 | 3654 | 4223 | 0.8652 | 0.7983 |
SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 2 | J09 | 72 | hr | 1401 | 4045 | 4223 | 0.9578 | 0.9369 |
SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1401 | 4404 | 4223 | 1.0428 | 1.0641 |
SK-BR-3 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1401 | 3319 | 4223 | 0.7859 | 0.6796 |
SK-BR-3 | Fedratinib | 1.11 | uM | LJP5 | 2 | L03 | 72 | hr | 1401 | 3470 | 4223 | 0.8217 | 0.7331 |
SK-BR-3 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1401 | 3536 | 4223 | 0.8373 | 0.7565 |
SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 1 | H21 | 72 | hr | 1401 | 3807 | 4223 | 0.9015 | 0.8525 |
SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 2 | H21 | 72 | hr | 1401 | 4013 | 4223 | 0.9503 | 0.9255 |
SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 3 | H21 | 72 | hr | 1401 | 4606 | 4223 | 1.0907 | 1.1357 |
SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 1 | O15 | 72 | hr | 1401 | 1508 | 4223 | 0.3571 | 0.0377 |
SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 2 | O15 | 72 | hr | 1401 | 1545 | 4223 | 0.3659 | 0.0508 |
SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 3 | O15 | 72 | hr | 1401 | 1485 | 4223 | 0.3516 | 0.0296 |
SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 1 | I21 | 72 | hr | 1401 | 1189 | 4223 | 0.2816 | -0.0753 |
SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 2 | I21 | 72 | hr | 1401 | 1188 | 4223 | 0.2813 | -0.0757 |
SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 3 | I21 | 72 | hr | 1401 | 1188 | 4223 | 0.2813 | -0.0757 |
SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 1 | B15 | 72 | hr | 1401 | 1412 | 4223 | 0.3344 | 0.0037 |
SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 2 | B15 | 72 | hr | 1401 | 1522 | 4223 | 0.3604 | 0.0427 |
SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 3 | B15 | 72 | hr | 1401 | 1420 | 4223 | 0.3363 | 0.0065 |
SK-BR-3 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1401 | 3002 | 4223 | 0.7109 | 0.5672 |
SK-BR-3 | Trametinib | 1.11 | uM | LJP5 | 2 | P21 | 72 | hr | 1401 | 3300 | 4223 | 0.7814 | 0.6728 |
SK-BR-3 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1401 | 3914 | 4223 | 0.9268 | 0.8905 |