LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Sirolimus
1.11
uM
LJP6
3
L15
72
hr
1401 2729 4223 0.6462 0.4705
SK-BR-3 Sorafenib
1.11
uM
LJP6
1
B09
72
hr
1401 4078 4223 0.9656 0.9486
SK-BR-3 Sorafenib
1.11
uM
LJP6
2
B09
72
hr
1401 3919 4223 0.9280 0.8922
SK-BR-3 Sorafenib
1.11
uM
LJP6
3
B09
72
hr
1401 4325 4223 1.0241 1.0361
SK-BR-3 SU11274
1.11
uM
LJP5
1
J09
72
hr
1401 3654 4223 0.8652 0.7983
SK-BR-3 SU11274
1.11
uM
LJP5
2
J09
72
hr
1401 4045 4223 0.9578 0.9369
SK-BR-3 SU11274
1.11
uM
LJP5
3
J09
72
hr
1401 4404 4223 1.0428 1.0641
SK-BR-3 Fedratinib
1.11
uM
LJP5
1
L03
72
hr
1401 3319 4223 0.7859 0.6796
SK-BR-3 Fedratinib
1.11
uM
LJP5
2
L03
72
hr
1401 3470 4223 0.8217 0.7331
SK-BR-3 Fedratinib
1.11
uM
LJP5
3
L03
72
hr
1401 3536 4223 0.8373 0.7565
SK-BR-3 TGX221
1.11
uM
LJP5
1
H21
72
hr
1401 3807 4223 0.9015 0.8525
SK-BR-3 TGX221
1.11
uM
LJP5
2
H21
72
hr
1401 4013 4223 0.9503 0.9255
SK-BR-3 TGX221
1.11
uM
LJP5
3
H21
72
hr
1401 4606 4223 1.0907 1.1357
SK-BR-3 Torin1
1.11
uM
LJP6
1
O15
72
hr
1401 1508 4223 0.3571 0.0377
SK-BR-3 Torin1
1.11
uM
LJP6
2
O15
72
hr
1401 1545 4223 0.3659 0.0508
SK-BR-3 Torin1
1.11
uM
LJP6
3
O15
72
hr
1401 1485 4223 0.3516 0.0296
SK-BR-3 Torin2
1.11
uM
LJP5
1
I21
72
hr
1401 1189 4223 0.2816 -0.0753
SK-BR-3 Torin2
1.11
uM
LJP5
2
I21
72
hr
1401 1188 4223 0.2813 -0.0757
SK-BR-3 Torin2
1.11
uM
LJP5
3
I21
72
hr
1401 1188 4223 0.2813 -0.0757
SK-BR-3 Tozasertib
1.11
uM
LJP5
1
B15
72
hr
1401 1412 4223 0.3344 0.0037
SK-BR-3 Tozasertib
1.11
uM
LJP5
2
B15
72
hr
1401 1522 4223 0.3604 0.0427
SK-BR-3 Tozasertib
1.11
uM
LJP5
3
B15
72
hr
1401 1420 4223 0.3363 0.0065
SK-BR-3 Trametinib
1.11
uM
LJP5
1
P21
72
hr
1401 3002 4223 0.7109 0.5672
SK-BR-3 Trametinib
1.11
uM
LJP5
2
P21
72
hr
1401 3300 4223 0.7814 0.6728
SK-BR-3 Trametinib
1.11
uM
LJP5
3
P21
72
hr
1401 3914 4223 0.9268 0.8905