LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 2 | K21 | 72 | hr | 1401 | 1399 | 4223 | 0.3313 | -0.0009 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1401 | 1448 | 4223 | 0.3429 | 0.0165 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 1 | E15 | 72 | hr | 1401 | 3620 | 4223 | 0.8572 | 0.7863 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 2 | E15 | 72 | hr | 1401 | 3856 | 4223 | 0.9131 | 0.8699 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 3 | E15 | 72 | hr | 1401 | 4291 | 4223 | 1.0161 | 1.0241 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 1 | L15 | 72 | hr | 1401 | 4588 | 4223 | 1.0864 | 1.1293 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 2 | L15 | 72 | hr | 1401 | 4671 | 4223 | 1.1061 | 1.1587 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 3 | L15 | 72 | hr | 1401 | 4884 | 4223 | 1.1565 | 1.2342 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 1 | K15 | 72 | hr | 1401 | 3324 | 4223 | 0.7871 | 0.6814 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 2 | K15 | 72 | hr | 1401 | 3683 | 4223 | 0.8721 | 0.8086 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 3 | K15 | 72 | hr | 1401 | 3468 | 4223 | 0.8212 | 0.7324 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 1 | C09 | 72 | hr | 1401 | 3755 | 4223 | 0.8892 | 0.8341 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 2 | C09 | 72 | hr | 1401 | 3063 | 4223 | 0.7253 | 0.5889 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 3 | C09 | 72 | hr | 1401 | 3087 | 4223 | 0.7310 | 0.5974 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1401 | 2682 | 4223 | 0.6351 | 0.4538 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1401 | 2923 | 4223 | 0.6922 | 0.5392 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1401 | 3143 | 4223 | 0.7442 | 0.6172 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 1 | H15 | 72 | hr | 1401 | 1349 | 4223 | 0.3194 | -0.0186 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 2 | H15 | 72 | hr | 1401 | 1760 | 4223 | 0.4168 | 0.1271 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 3 | H15 | 72 | hr | 1401 | 1637 | 4223 | 0.3876 | 0.0835 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 1 | I21 | 72 | hr | 1401 | 1030 | 4223 | 0.2439 | -0.1317 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 2 | I21 | 72 | hr | 1401 | 1054 | 4223 | 0.2496 | -0.1232 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 3 | I21 | 72 | hr | 1401 | 1225 | 4223 | 0.2901 | -0.0626 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 1 | E09 | 72 | hr | 1401 | 1882 | 4223 | 0.4457 | 0.1703 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 2 | E09 | 72 | hr | 1401 | 1549 | 4223 | 0.3668 | 0.0523 |