LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 R406
0.37
uM
LJP6
1
C16
72
hr
1401 4063 4223 0.9621 0.9433
SK-BR-3 R406
0.37
uM
LJP6
2
C16
72
hr
1401 4336 4223 1.0267 1.0400
SK-BR-3 R406
0.37
uM
LJP6
3
C16
72
hr
1401 3938 4223 0.9325 0.8990
SK-BR-3 Pictilisib
0.37
uM
LJP6
1
D22
72
hr
1401 1994 4223 0.4722 0.2100
SK-BR-3 Pictilisib
0.37
uM
LJP6
2
D22
72
hr
1401 1792 4223 0.4243 0.1384
SK-BR-3 Pictilisib
0.37
uM
LJP6
3
D22
72
hr
1401 1808 4223 0.4281 0.1441
SK-BR-3 Gefitinib
0.37
uM
LJP6
1
N10
72
hr
1401 3235 4223 0.7660 0.6498
SK-BR-3 Gefitinib
0.37
uM
LJP6
2
N10
72
hr
1401 2918 4223 0.6910 0.5375
SK-BR-3 Gefitinib
0.37
uM
LJP6
3
N10
72
hr
1401 3128 4223 0.7407 0.6119
SK-BR-3 Geldanamycin
0.37
uM
LJP5
1
O04
72
hr
1401 1204 4223 0.2851 -0.0700
SK-BR-3 Geldanamycin
0.37
uM
LJP5
2
O04
72
hr
1401 1610 4223 0.3812 0.0739
SK-BR-3 Geldanamycin
0.37
uM
LJP5
3
O04
72
hr
1401 1653 4223 0.3914 0.0891
SK-BR-3 Geldanamycin
0.37
uM
LJP6
1
O04
72
hr
1401 1573 4223 0.3725 0.0608
SK-BR-3 Geldanamycin
0.37
uM
LJP6
2
O04
72
hr
1401 1393 4223 0.3299 -0.0030
SK-BR-3 Geldanamycin
0.37
uM
LJP6
3
O04
72
hr
1401 1393 4223 0.3299 -0.0030
SK-BR-3 GSK1059615
0.37
uM
LJP5
1
E04
72
hr
1401 2855 4223 0.6761 0.5151
SK-BR-3 GSK1059615
0.37
uM
LJP5
2
E04
72
hr
1401 2900 4223 0.6867 0.5311
SK-BR-3 GSK1059615
0.37
uM
LJP5
3
E04
72
hr
1401 3207 4223 0.7594 0.6399
SK-BR-3 GSK1059615
0.37
uM
LJP6
1
C04
72
hr
1401 3104 4223 0.7350 0.6034
SK-BR-3 GSK1059615
0.37
uM
LJP6
2
C04
72
hr
1401 2985 4223 0.7068 0.5612
SK-BR-3 GSK1059615
0.37
uM
LJP6
3
C04
72
hr
1401 3006 4223 0.7118 0.5687
SK-BR-3 GSK1904529A
0.37
uM
LJP6
1
H22
72
hr
1401 4194 4223 0.9931 0.9897
SK-BR-3 GSK1904529A
0.37
uM
LJP6
2
H22
72
hr
1401 3850 4223 0.9117 0.8678
SK-BR-3 GSK1904529A
0.37
uM
LJP6
3
H22
72
hr
1401 4096 4223 0.9699 0.9550
SK-BR-3 Omipalisib
0.37
uM
LJP6
1
N04
72
hr
1401 1211 4223 0.2868 -0.0675