LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Mitoxantrone
3.33
uM
LJP5
1
C20
72
hr
1401 864 4223 0.2046 -0.1905
SK-BR-3 Mitoxantrone
3.33
uM
LJP5
2
C20
72
hr
1401 733 4223 0.1736 -0.2369
SK-BR-3 Mitoxantrone
3.33
uM
LJP5
3
C20
72
hr
1401 793 4223 0.1878 -0.2157
SK-BR-3 Mitoxantrone
3.33
uM
LJP6
1
C20
72
hr
1401 693 4223 0.1641 -0.2511
SK-BR-3 Mitoxantrone
3.33
uM
LJP6
2
C20
72
hr
1401 598 4223 0.1416 -0.2848
SK-BR-3 Mitoxantrone
3.33
uM
LJP6
3
C20
72
hr
1401 787 4223 0.1864 -0.2178
SK-BR-3 MK2206
3.33
uM
LJP6
1
F02
72
hr
1401 2156 4223 0.5105 0.2674
SK-BR-3 MK2206
3.33
uM
LJP6
2
F02
72
hr
1401 2194 4223 0.5195 0.2809
SK-BR-3 MK2206
3.33
uM
LJP6
3
F02
72
hr
1401 2205 4223 0.5221 0.2848
SK-BR-3 Neratinib
3.33
uM
LJP5
1
A14
72
hr
1401 1413 4223 0.3346 0.0041
SK-BR-3 Neratinib
3.33
uM
LJP5
2
A14
72
hr
1401 1549 4223 0.3668 0.0523
SK-BR-3 Neratinib
3.33
uM
LJP5
3
A14
72
hr
1401 1285 4223 0.3043 -0.0413
SK-BR-3 Nilotinib
3.33
uM
LJP5
1
N14
72
hr
1401 4421 4223 1.0469 1.0701
SK-BR-3 Nilotinib
3.33
uM
LJP5
2
N14
72
hr
1401 4912 4223 1.1631 1.2442
SK-BR-3 Nilotinib
3.33
uM
LJP5
3
N14
72
hr
1401 4890 4223 1.1579 1.2364
SK-BR-3 Nintedanib
3.33
uM
LJP6
1
H02
72
hr
1401 3370 4223 0.7980 0.6977
SK-BR-3 Nintedanib
3.33
uM
LJP6
2
H02
72
hr
1401 3285 4223 0.7779 0.6675
SK-BR-3 Nintedanib
3.33
uM
LJP6
3
H02
72
hr
1401 3184 4223 0.7540 0.6317
SK-BR-3 NU7441
3.33
uM
LJP5
1
C08
72
hr
1401 3772 4223 0.8932 0.8401
SK-BR-3 NU7441
3.33
uM
LJP5
2
C08
72
hr
1401 3049 4223 0.7220 0.5839
SK-BR-3 NU7441
3.33
uM
LJP5
3
C08
72
hr
1401 3011 4223 0.7130 0.5704
SK-BR-3 Dactolisib
3.33
uM
LJP5
1
M14
72
hr
1401 1612 4223 0.3817 0.0746
SK-BR-3 Dactolisib
3.33
uM
LJP5
2
M14
72
hr
1401 1556 4223 0.3685 0.0547
SK-BR-3 Dactolisib
3.33
uM
LJP5
3
M14
72
hr
1401 1514 4223 0.3585 0.0399
SK-BR-3 NVP-TAE684
3.33
uM
LJP6
1
K14
72
hr
1401 2127 4223 0.5037 0.2571