LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 QL-XII-47
1.11
uM
LJP6
2
O21
72
hr
1401 1607 4223 0.3805 0.0728
SK-BR-3 QL-XII-47
1.11
uM
LJP6
3
O21
72
hr
1401 1393 4223 0.3299 -0.0030
SK-BR-3 Radicicol
1.11
uM
LJP5
1
K09
72
hr
1401 2317 4223 0.5487 0.3245
SK-BR-3 Radicicol
1.11
uM
LJP5
2
K09
72
hr
1401 1295 4223 0.3067 -0.0378
SK-BR-3 Radicicol
1.11
uM
LJP5
3
K09
72
hr
1401 1345 4223 0.3185 -0.0200
SK-BR-3 Radicicol
1.11
uM
LJP6
1
K09
72
hr
1401 1534 4223 0.3632 0.0470
SK-BR-3 Radicicol
1.11
uM
LJP6
2
K09
72
hr
1401 1468 4223 0.3476 0.0236
SK-BR-3 Radicicol
1.11
uM
LJP6
3
K09
72
hr
1401 1495 4223 0.3540 0.0331
SK-BR-3 Seliciclib
1.11
uM
LJP5
1
J03
72
hr
1401 3597 4223 0.8518 0.7781
SK-BR-3 Seliciclib
1.11
uM
LJP5
2
J03
72
hr
1401 3624 4223 0.8581 0.7877
SK-BR-3 Seliciclib
1.11
uM
LJP5
3
J03
72
hr
1401 4068 4223 0.9633 0.9450
SK-BR-3 Ruxolitinib
1.11
uM
LJP5
1
O15
72
hr
1401 3901 4223 0.9237 0.8859
SK-BR-3 Ruxolitinib
1.11
uM
LJP5
2
O15
72
hr
1401 4257 4223 1.0080 1.0120
SK-BR-3 Ruxolitinib
1.11
uM
LJP5
3
O15
72
hr
1401 4189 4223 0.9919 0.9879
SK-BR-3 XL147
1.11
uM
LJP5
1
G09
72
hr
1401 4963 4223 1.1752 1.2622
SK-BR-3 XL147
1.11
uM
LJP5
2
G09
72
hr
1401 5030 4223 1.1911 1.2860
SK-BR-3 XL147
1.11
uM
LJP5
3
G09
72
hr
1401 4839 4223 1.1458 1.2183
SK-BR-3 Saracatinib
1.11
uM
LJP6
1
D09
72
hr
1401 4059 4223 0.9611 0.9418
SK-BR-3 Saracatinib
1.11
uM
LJP6
2
D09
72
hr
1401 4147 4223 0.9820 0.9730
SK-BR-3 Saracatinib
1.11
uM
LJP6
3
D09
72
hr
1401 4338 4223 1.0272 1.0407
SK-BR-3 Selumetinib
1.11
uM
LJP6
1
M09
72
hr
1401 4023 4223 0.9526 0.9291
SK-BR-3 Selumetinib
1.11
uM
LJP6
2
M09
72
hr
1401 3897 4223 0.9228 0.8844
SK-BR-3 Selumetinib
1.11
uM
LJP6
3
M09
72
hr
1401 4222 4223 0.9997 0.9996
SK-BR-3 Sirolimus
1.11
uM
LJP6
1
L15
72
hr
1401 2530 4223 0.5991 0.4000
SK-BR-3 Sirolimus
1.11
uM
LJP6
2
L15
72
hr
1401 2647 4223 0.6268 0.4414