LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Lapatinib | 3.33 | uM | LJP6 | 3 | M20 | 72 | hr | 1235 | 4310 | 4156 | 1.0370 | 1.0527 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 1 | G02 | 72 | hr | 1235 | 2105 | 4156 | 0.5065 | 0.2977 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 2 | G02 | 72 | hr | 1235 | 2402 | 4156 | 0.5779 | 0.3994 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 3 | G02 | 72 | hr | 1235 | 2066 | 4156 | 0.4971 | 0.2844 |
| MCF7 | Linifanib | 3.33 | uM | LJP6 | 1 | J08 | 72 | hr | 1235 | 3850 | 4156 | 0.9263 | 0.8952 |
| MCF7 | Linifanib | 3.33 | uM | LJP6 | 2 | J08 | 72 | hr | 1235 | 4064 | 4156 | 0.9778 | 0.9684 |
| MCF7 | Linifanib | 3.33 | uM | LJP6 | 3 | J08 | 72 | hr | 1235 | 3614 | 4156 | 0.8696 | 0.8144 |
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 1 | O20 | 72 | hr | 1235 | 1988 | 4156 | 0.4783 | 0.2577 |
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 2 | O20 | 72 | hr | 1235 | 2102 | 4156 | 0.5058 | 0.2967 |
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 3 | O20 | 72 | hr | 1235 | 2472 | 4156 | 0.5948 | 0.4234 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 1235 | 642 | 4156 | 0.1545 | -0.2032 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 1235 | 587 | 4156 | 0.1412 | -0.2220 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 1235 | 636 | 4156 | 0.1530 | -0.2052 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 1235 | 593 | 4156 | 0.1427 | -0.2199 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 1235 | 717 | 4156 | 0.1725 | -0.1775 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 1235 | 671 | 4156 | 0.1615 | -0.1932 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 1 | F02 | 72 | hr | 1235 | 1224 | 4156 | 0.2945 | -0.0039 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 2 | F02 | 72 | hr | 1235 | 1577 | 4156 | 0.3794 | 0.1170 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 3 | F02 | 72 | hr | 1235 | 1442 | 4156 | 0.3470 | 0.0707 |
| MCF7 | Neratinib | 3.33 | uM | LJP5 | 1 | A14 | 72 | hr | 1235 | 1999 | 4156 | 0.4810 | 0.2614 |
| MCF7 | Neratinib | 3.33 | uM | LJP5 | 2 | A14 | 72 | hr | 1235 | 2169 | 4156 | 0.5219 | 0.3197 |
| MCF7 | Neratinib | 3.33 | uM | LJP5 | 3 | A14 | 72 | hr | 1235 | 1926 | 4156 | 0.4634 | 0.2365 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 1 | N14 | 72 | hr | 1235 | 3983 | 4156 | 0.9583 | 0.9407 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 2 | N14 | 72 | hr | 1235 | 4674 | 4156 | 1.1246 | 1.1773 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 3 | N14 | 72 | hr | 1235 | 4392 | 4156 | 1.0567 | 1.0807 |