LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 1 | H07 | 72 | hr | 1235 | 418 | 4156 | 0.1006 | -0.2799 |
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 2 | H07 | 72 | hr | 1235 | 419 | 4156 | 0.1008 | -0.2795 |
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 3 | H07 | 72 | hr | 1235 | 454 | 4156 | 0.1092 | -0.2675 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 1 | G07 | 72 | hr | 1235 | 1018 | 4156 | 0.2449 | -0.0744 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 2 | G07 | 72 | hr | 1235 | 978 | 4156 | 0.2353 | -0.0881 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 3 | G07 | 72 | hr | 1235 | 1157 | 4156 | 0.2784 | -0.0268 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 1 | F01 | 72 | hr | 1235 | 681 | 4156 | 0.1639 | -0.1898 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 2 | F01 | 72 | hr | 1235 | 619 | 4156 | 0.1489 | -0.2110 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 3 | F01 | 72 | hr | 1235 | 711 | 4156 | 0.1711 | -0.1795 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 1 | G01 | 72 | hr | 1235 | 364 | 4156 | 0.0876 | -0.2983 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 2 | G01 | 72 | hr | 1235 | 398 | 4156 | 0.0958 | -0.2867 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 3 | G01 | 72 | hr | 1235 | 388 | 4156 | 0.0934 | -0.2901 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 1 | P13 | 72 | hr | 1235 | 1770 | 4156 | 0.4259 | 0.1830 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 2 | P13 | 72 | hr | 1235 | 1372 | 4156 | 0.3301 | 0.0468 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 3 | P13 | 72 | hr | 1235 | 1730 | 4156 | 0.4163 | 0.1693 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1235 | 2139 | 4156 | 0.5147 | 0.3094 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1235 | 2057 | 4156 | 0.4949 | 0.2813 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1235 | 2135 | 4156 | 0.5137 | 0.3080 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 1 | I07 | 72 | hr | 1235 | 1943 | 4156 | 0.4675 | 0.2423 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 2 | I07 | 72 | hr | 1235 | 1881 | 4156 | 0.4526 | 0.2210 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 3 | I07 | 72 | hr | 1235 | 2092 | 4156 | 0.5034 | 0.2933 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 1 | A19 | 72 | hr | 1235 | 666 | 4156 | 0.1602 | -0.1949 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 2 | A19 | 72 | hr | 1235 | 792 | 4156 | 0.1906 | -0.1518 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 3 | A19 | 72 | hr | 1235 | 792 | 4156 | 0.1906 | -0.1518 |
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 1 | P07 | 72 | hr | 1235 | 1430 | 4156 | 0.3441 | 0.0666 |