LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 2 | P07 | 72 | hr | 1235 | 1397 | 4156 | 0.3361 | 0.0553 |
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 3 | P07 | 72 | hr | 1235 | 1407 | 4156 | 0.3385 | 0.0588 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 1 | D01 | 72 | hr | 1235 | 837 | 4156 | 0.2014 | -0.1364 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 2 | D01 | 72 | hr | 1235 | 955 | 4156 | 0.2298 | -0.0960 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 3 | D01 | 72 | hr | 1235 | 963 | 4156 | 0.2317 | -0.0933 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 1 | I01 | 72 | hr | 1235 | 767 | 4156 | 0.1846 | -0.1604 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 2 | I01 | 72 | hr | 1235 | 802 | 4156 | 0.1930 | -0.1484 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 3 | I01 | 72 | hr | 1235 | 790 | 4156 | 0.1901 | -0.1525 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 1 | E19 | 72 | hr | 1235 | 2211 | 4156 | 0.5320 | 0.3340 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 2 | E19 | 72 | hr | 1235 | 2210 | 4156 | 0.5317 | 0.3337 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 3 | E19 | 72 | hr | 1235 | 2170 | 4156 | 0.5221 | 0.3200 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 1 | D13 | 72 | hr | 1235 | 2356 | 4156 | 0.5669 | 0.3837 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 2 | D13 | 72 | hr | 1235 | 2309 | 4156 | 0.5556 | 0.3676 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 3 | D13 | 72 | hr | 1235 | 2272 | 4156 | 0.5467 | 0.3549 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 1 | M19 | 72 | hr | 1235 | 4103 | 4156 | 0.9872 | 0.9818 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 2 | M19 | 72 | hr | 1235 | 4302 | 4156 | 1.0351 | 1.0499 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 3 | M19 | 72 | hr | 1235 | 4400 | 4156 | 1.0587 | 1.0835 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 1 | H07 | 72 | hr | 1235 | 718 | 4156 | 0.1728 | -0.1771 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 2 | H07 | 72 | hr | 1235 | 904 | 4156 | 0.2175 | -0.1135 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 3 | H07 | 72 | hr | 1235 | 897 | 4156 | 0.2158 | -0.1159 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 1 | C13 | 72 | hr | 1235 | 1734 | 4156 | 0.4172 | 0.1707 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 2 | C13 | 72 | hr | 1235 | 1672 | 4156 | 0.4023 | 0.1495 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 3 | C13 | 72 | hr | 1235 | 1863 | 4156 | 0.4483 | 0.2149 |
| MCF7 | Pictilisib | 10.0 | uM | LJP6 | 1 | D19 | 72 | hr | 1235 | 1151 | 4156 | 0.2769 | -0.0289 |
| MCF7 | Pictilisib | 10.0 | uM | LJP6 | 2 | D19 | 72 | hr | 1235 | 1145 | 4156 | 0.2755 | -0.0309 |