LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 AZD7762
0.04
uM
LJP6
 3
L06
 72
hr
 868 2185 3486 0.6267 0.5030
MDA-MB-231 AZD8055
0.04
uM
LJP6
 1
A12
 72
hr
 868 2119 3486 0.6078 0.4778
MDA-MB-231 AZD8055
0.04
uM
LJP6
 2
A12
 72
hr
 868 1593 3486 0.4569 0.2769
MDA-MB-231 AZD8055
0.04
uM
LJP6
 3
A12
 72
hr
 868 1691 3486 0.4850 0.3143
MDA-MB-231 AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 868 966 3486 0.2771 0.0374
MDA-MB-231 AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 868 1032 3486 0.2960 0.0626
MDA-MB-231 AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 868 821 3486 0.2355 -0.0180
MDA-MB-231 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 868 1375 3486 0.3944 0.1936
MDA-MB-231 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 868 1365 3486 0.3915 0.1898
MDA-MB-231 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 868 1521 3486 0.4363 0.2494
MDA-MB-231 BI-2536
0.04
uM
LJP6
 1
D18
 72
hr
 868 1160 3486 0.3327 0.1115
MDA-MB-231 BI-2536
0.04
uM
LJP6
 2
D18
 72
hr
 868 1160 3486 0.3327 0.1115
MDA-MB-231 BI-2536
0.04
uM
LJP6
 3
D18
 72
hr
 868 1194 3486 0.3425 0.1245
MDA-MB-231 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 868 3747 3486 1.0747 1.0995
MDA-MB-231 BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 868 3445 3486 0.9881 0.9842
MDA-MB-231 BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 868 3471 3486 0.9956 0.9941
MDA-MB-231 SNS-032
0.04
uM
LJP6
 1
H18
 72
hr
 868 1211 3486 0.3474 0.1310
MDA-MB-231 SNS-032
0.04
uM
LJP6
 2
H18
 72
hr
 868 1317 3486 0.3778 0.1714
MDA-MB-231 SNS-032
0.04
uM
LJP6
 3
H18
 72
hr
 868 1192 3486 0.3419 0.1237
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 868 2518 3486 0.7222 0.6301
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 868 2480 3486 0.7113 0.6156
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 868 2342 3486 0.6718 0.5629
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 868 3664 3486 1.0509 1.0678
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 868 3351 3486 0.9612 0.9483
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 868 3580 3486 1.0268 1.0357