LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 YM 201636
10.0
uM
LJP5
 2
N07
 72
hr
 1235 1882 4156 0.4528 0.2214
MCF7 YM 201636
10.0
uM
LJP5
 3
N07
 72
hr
 1235 1746 4156 0.4201 0.1748
MCF7 ZSTK474
10.0
uM
LJP6
 1
M13
 72
hr
 1235 1469 4156 0.3535 0.0800
MCF7 ZSTK474
10.0
uM
LJP6
 2
M13
 72
hr
 1235 1220 4156 0.2935 -0.0053
MCF7 ZSTK474
10.0
uM
LJP6
 3
M13
 72
hr
 1235 1327 4156 0.3193 0.0314
MDA-MB-231 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 868 2415 3486 0.6927 0.5908
MDA-MB-231 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 868 2747 3486 0.7879 0.7176
MDA-MB-231 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 868 2487 3486 0.7133 0.6183
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 868 2439 3486 0.6996 0.6000
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 868 2794 3486 0.8014 0.7356
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 868 2982 3486 0.8553 0.8074
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 1
A18
 72
hr
 868 1231 3486 0.3531 0.1386
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 2
A18
 72
hr
 868 1272 3486 0.3649 0.1543
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 3
A18
 72
hr
 868 1209 3486 0.3468 0.1302
MDA-MB-231 AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 868 2847 3486 0.8166 0.7558
MDA-MB-231 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 868 3217 3486 0.9227 0.8971
MDA-MB-231 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 868 3457 3486 0.9916 0.9888
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 868 3175 3486 0.9107 0.8811
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 868 3385 3486 0.9709 0.9613
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 868 3578 3486 1.0263 1.0350
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 868 2923 3486 0.8384 0.7848
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 868 3511 3486 1.0071 1.0094
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 868 3100 3486 0.8892 0.8524
MDA-MB-231 AZD7762
0.04
uM
LJP6
 1
L06
 72
hr
 868 1815 3486 0.5206 0.3616
MDA-MB-231 AZD7762
0.04
uM
LJP6
 2
L06
 72
hr
 868 2177 3486 0.6244 0.4999