LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | TWS119 | 10.0 | uM | LJP5 | 1 | M01 | 72 | hr | 1235 | 747 | 4156 | 0.1797 | -0.1672 |
| MCF7 | TWS119 | 10.0 | uM | LJP5 | 2 | M01 | 72 | hr | 1235 | 636 | 4156 | 0.1530 | -0.2052 |
| MCF7 | TWS119 | 10.0 | uM | LJP5 | 3 | M01 | 72 | hr | 1235 | 811 | 4156 | 0.1951 | -0.1453 |
| MCF7 | Vemurafenib | 10.0 | uM | LJP5 | 1 | C13 | 72 | hr | 1235 | 3598 | 4156 | 0.8657 | 0.8089 |
| MCF7 | Vemurafenib | 10.0 | uM | LJP5 | 2 | C13 | 72 | hr | 1235 | 3448 | 4156 | 0.8296 | 0.7575 |
| MCF7 | Vemurafenib | 10.0 | uM | LJP5 | 3 | C13 | 72 | hr | 1235 | 3412 | 4156 | 0.8210 | 0.7452 |
| MCF7 | Withaferin A | 10.0 | uM | LJP5 | 1 | G13 | 72 | hr | 1235 | 956 | 4156 | 0.2300 | -0.0957 |
| MCF7 | Withaferin A | 10.0 | uM | LJP5 | 2 | G13 | 72 | hr | 1235 | 1102 | 4156 | 0.2652 | -0.0457 |
| MCF7 | Withaferin A | 10.0 | uM | LJP5 | 3 | G13 | 72 | hr | 1235 | 1275 | 4156 | 0.3068 | 0.0136 |
| MCF7 | Withaferin A | 10.0 | uM | LJP6 | 1 | G13 | 72 | hr | 1235 | 1051 | 4156 | 0.2529 | -0.0631 |
| MCF7 | Withaferin A | 10.0 | uM | LJP6 | 2 | G13 | 72 | hr | 1235 | 1060 | 4156 | 0.2550 | -0.0600 |
| MCF7 | Withaferin A | 10.0 | uM | LJP6 | 3 | G13 | 72 | hr | 1235 | 987 | 4156 | 0.2375 | -0.0850 |
| MCF7 | WYE-125132 | 10.0 | uM | LJP6 | 1 | L07 | 72 | hr | 1235 | 1389 | 4156 | 0.3342 | 0.0526 |
| MCF7 | WYE-125132 | 10.0 | uM | LJP6 | 2 | L07 | 72 | hr | 1235 | 1381 | 4156 | 0.3323 | 0.0499 |
| MCF7 | WYE-125132 | 10.0 | uM | LJP6 | 3 | L07 | 72 | hr | 1235 | 1411 | 4156 | 0.3395 | 0.0601 |
| MCF7 | WZ3105 | 10.0 | uM | LJP5 | 1 | D19 | 72 | hr | 1235 | 744 | 4156 | 0.1790 | -0.1682 |
| MCF7 | WZ3105 | 10.0 | uM | LJP5 | 2 | D19 | 72 | hr | 1235 | 791 | 4156 | 0.1903 | -0.1522 |
| MCF7 | WZ3105 | 10.0 | uM | LJP5 | 3 | D19 | 72 | hr | 1235 | 614 | 4156 | 0.1477 | -0.2128 |
| MCF7 | XMD11-50 | 10.0 | uM | LJP6 | 1 | P07 | 72 | hr | 1235 | 1362 | 4156 | 0.3277 | 0.0434 |
| MCF7 | XMD11-50 | 10.0 | uM | LJP6 | 2 | P07 | 72 | hr | 1235 | 1311 | 4156 | 0.3154 | 0.0259 |
| MCF7 | XMD11-50 | 10.0 | uM | LJP6 | 3 | P07 | 72 | hr | 1235 | 1308 | 4156 | 0.3147 | 0.0249 |
| MCF7 | Y39983 | 10.0 | uM | LJP6 | 1 | P01 | 72 | hr | 1235 | 547 | 4156 | 0.1316 | -0.2357 |
| MCF7 | Y39983 | 10.0 | uM | LJP6 | 2 | P01 | 72 | hr | 1235 | 697 | 4156 | 0.1677 | -0.1843 |
| MCF7 | Y39983 | 10.0 | uM | LJP6 | 3 | P01 | 72 | hr | 1235 | 622 | 4156 | 0.1497 | -0.2100 |
| MCF7 | YM 201636 | 10.0 | uM | LJP5 | 1 | N07 | 72 | hr | 1235 | 1799 | 4156 | 0.4329 | 0.1930 |